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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Inflammation profile in overweight/obese adolescents in Europe: an analysis in relation to iron status

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Autor(es):
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Ferrari, M. [1] ; Cuenca-Garcia, M. [2] ; Valtuena, J. [1, 3] ; Moreno, L. A. [4] ; Censi, L. [1] ; Gonzalez-Gross, M. [3, 5] ; Androutsos, O. [6] ; Gilbert, C. C. [7] ; Huybrechts, I. [8] ; Dallongeville, J. [9] ; Sjostrom, M. [10] ; Molnar, D. [11] ; De Henauw, S. [12, 13] ; Gomez-Martinez, S. [14] ; de Moraes, A. C. F. [4, 15] ; Kafatos, A. [16] ; Widhalm, K. [17] ; Leclercq, C. [1] ; Grp, HELENA Study
Número total de Autores: 19
Afiliação do(s) autor(es):
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[1] Food & Nutr Res Ctr, Agr Res Council, CRA NUT, I-00178 Rome - Italy
[2] Univ Granada, Sch Med, Dept Med Physiol, Granada - Spain
[3] Univ Politecn Madrid, ImFine Res Grp, Dept Hlth & Human Performance, Fac Ciencias Actividad Fis & Deporte INEF, Madrid - Spain
[4] Univ Zaragoza, EU Ciencias Salud, GENUD Growth Exercise Nutr & Dev Res Grp, Zaragoaza - Spain
[5] Univ Bonn, Dept Nutr & Food Sci Nutr Physiol, Bonn - Germany
[6] Harakopio Univ, Dept Nutr & Dietet, Athens - Greece
[7] Campden BRI, Dept Consumer & Sensory Sci, Chipping Campden, Glos - England
[8] Int Agcy Res Canc, Dietary Exposure Assessment Grp, F-69372 Lyon - France
[9] Univ Lille Nord France, Inst Pasteur Lille, INSERM, U744, Lille - France
[10] Karolinska Inst, Dept Biosci & Nutr, Huddinge - Sweden
[11] Univ Pecs, Dept Paediat, Pecs - Hungary
[12] Univ Ghent, Dept Publ Hlth, Univ Hosp, B-9000 Ghent - Belgium
[13] Univ Coll Ghent, Dept Nutr & Dietet, Fac Hlth Care Vesalius, Ghent - Belgium
[14] Spanish Council Sci Res CSIC, Dept Metab & Nutr, Immunonutr Res Grp, Madrid - Spain
[15] Univ Sao Paulo, Sch Med, Postgrad Program Sci, Dept Prevent Med, Sao Paulo - Brazil
[16] Univ Crete, Sch Med, Dept Social Med, Prevent Med & Nutr Clin, Iraklion - Greece
[17] Private Med Univ Salzburg, Div Clin Nutr, Dept Paediat & Adolescents Med, Salzburg - Austria
Número total de Afiliações: 17
Tipo de documento: Artigo Científico
Fonte: European Journal of Clinical Nutrition; v. 69, n. 2, p. 247-255, FEB 2015.
Citações Web of Science: 16
Resumo

BACKGROUND/OBJECTIVES: The objectives of this study were to investigate the relationship between inflammatory parameters (CRP, c-reactive protein; AGP, alpha 1-acid glycoprotein), iron status indicators (SF, serum ferritin; sTfR, soluble transferrin receptor) and body mass index (BMI) z-score, fat-free mass (FFM) and fat mass (FM) in European adolescents. Differences in intake for some nutrients (total iron, haem and non-haem iron, vitamin C, calcium, proteins) were assessed according to BMI categories, and the association of nutrient intakes with BMI z-score, FM and FFM was evaluated. METHODS: A total of 876 adolescents participating in the Healthy Lifestyle in Europe by Nutrition in Adolescence-Cross Sectional Study were included in the study sample. RESULTS: Mean CRP values (standard error; s.e.) were significantly higher in overweight/obese adolescents (1.7 +/- 0.3 and 1.4 +/- 0.3 mg/l in boys and girls, respectively) than in thin/normal-weight adolescents (1.1 +/- 0.2 and 1.0 +/- 0.1 mg/l in boys and girls, respectively) (P < 0.05). For boys, mean SF values (s.e.) were significantly higher in overweight/obese adolescents (46.9 +/- 2.7 mu g/l) than in thin/normal-weight adolescents (35.7 +/- 1.7 mu g/l) (P < 0.001), whereas median sTfR values did not differ among BMI categories for both boys and girls. Multilevel regression analyses showed that BMI z-score and FM were significantly related to CRP and AGP (P < 0.05). Dietary variables did not differ significantly among BMI categories, except for the intake of vegetable proteins, which, for boys, was higher in thin/normal-weight adolescents than in overweight/obese adolescents (P < 0.05). CONCLUSIONS: The adiposity of the European adolescents was sufficient to cause chronic inflammation but not sufficient to impair iron status and cause iron deficiency. (AU)

Processo FAPESP: 11/11137-1 - Pressão arterial elevada e agregação de fatores de risco em adolescentes: um estudo multicêntrico
Beneficiário:Augusto César Ferreira de Moraes
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 11/20662-2 - Pressão arterial elevada e agregação de fatores de risco em adolescentes: um estudo multicêntrico
Beneficiário:Augusto César Ferreira de Moraes
Linha de fomento: Bolsas no Exterior - Estágio de Pesquisa - Doutorado