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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

ORIGIN AND PREVALENCE OF HUMAN T-LYMPHOTROPIC VIRUS TYPE 1 (HTLV-1) AND TYPE 2 (HTLV-2) AMONG INDIGENOUS POPULATIONS IN THE AMERICAS

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Autor(es):
Paiva, Arthur [1, 2] ; Casseb, Jorge [2]
Número total de Autores: 2
Afiliação do(s) autor(es):
[1] Univ Fed Alagoas, Univ Hosp, Maceio, Alagoas - Brazil
[2] Univ Sao Paulo, Inst Trop Med Sao Paulo, Sao Paulo - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo de Revisão
Fonte: Revista do Instituto de Medicina Tropical de São Paulo; v. 57, n. 1, p. 1-13, JAN-FEB 2015.
Citações Web of Science: 20
Resumo

Human T-lymphotropic virus type 1 (HTLV-1) is found in indigenous peoples of the Pacific Islands and the Americas, whereas type 2 (HTLV-2) is widely distributed among the indigenous peoples of the Americas, where it appears to be more prevalent than HTLV-1, and in some tribes of Central Africa. HTLV-2 is considered ancestral in the Americas and is transmitted to the general population and injection drug users from the indigenous population. In the Americas, HTLV-1 has more than one origin, being brought by immigrants in the Paleolithic period through the Bering Strait, through slave trade during the colonial period, and through Japanese immigration from the early 20(th) century, whereas HTLV-2 was only brought by immigrants through the Bering Strait. The endemicity of HTLV-2 among the indigenous people of Brazil makes the Brazilian Amazon the largest endemic area in the world for its occurrence. A review of HTLV-1 in all Brazilian tribes supports the African origin of HTLV-1 in Brazil. The risk of hyperendemicity in these epidemiologically closed populations and transmission to other populations reinforces the importance of public health interventions for HTLV control, including the recognition of the infection among reportable diseases and events. (AU)

Processo FAPESP: 12/23397-0 - Determinação do perfil do polimorfismo da IL28B em indivíduos co-infectados pelo Vírus da Hepatite C crônica (HCV) e pelo vírus linfotrópico de células T humanas tipo 1 (HTLV-1)
Beneficiário:Jorge Simão do Rosário Casseb
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 08/56427-4 - Diversidade molecular do envelope e carga proviral do vírus linfotrópico de células T humanas tipo 2 (HTLV-2) em amotras indeterminadas pelo teste western-blot
Beneficiário:Jorge Simão do Rosário Casseb
Linha de fomento: Auxílio à Pesquisa - Regular