Sialidase Production and Genetic Diversity in Clostridium perfringens Type A Isolated from Chicken with Necrotic Enteritis in Brazil

Autor(es)

Llanco, Luis A. ^[1] ; Nakano, Viviane ^[1] ; Avila-Campos, Mario J. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Anaerobe Lab, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Current Microbiology; v. 70, n. 3, p. 330-337, MAR 2015.
• Citações Web of Science: 6

Resumo

The sialidase activity and genetic diversity of 22 Clostridium perfringens strains isolated from chickens with necrotic enteritis were determined. Sialidase activity was detected in 86.4 % of the strains. All C. perfringens showed a high value of similarity (>96 %), and they were grouped into seven clusters clearly separated from the other reference bacterial strains. From these clusters four patterns were defined in accordance with their phenotypic (sialidase production and antibiotic resistance profile) and genotypic (presence of nanI and nanJ genes) characteristics. Our results showed heterogeneity among strains, but they were genotypically similar, and it is suggested further studies are needed to better understand the pathogenesis of necrotic enteritis. (AU)

• Processo FAPESP: 09/03792-0 - Expressão dos genes bmeABC de bombas de efluxo de Bacteroides fragilis em Escherichia coli, caracterização do perfil de substrato das bombas bmeABC e sua relação com a resistência aos antimicrobianos
• Beneficiário: Viviane Nakano
• Modalidade de apoio: Bolsas no Brasil - Jovens Pesquisadores
• Processo FAPESP: 10/52417-4 - Possíveis impactos das gastroplastias sobre a microbiota periodontal de pacientes com obesidade: determinação do perfil microbiológico e imunológico
• Beneficiário: Mario Júlio Ávila-Campos
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/17739-9 - Avaliação clonal de cepas de Clostridium perfringens isolados de humanos e animais por Multilocus sequence typing (MLST)
• Beneficiário: Mario Júlio Ávila-Campos
• Modalidade de apoio: Auxílio à Pesquisa - Regular