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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Patterns of seizure control in patients with mesial temporal lobe epilepsy with and without hippocampus sclerosis

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Autor(es):
Coan, Ana Carolina [1] ; Campos, Brunno M. [1] ; Bergo, Felipe P. G. [1] ; Kubota, Bruno Y. [1] ; Yasuda, Clarissa L. [1] ; Morita, Marcia E. [1] ; Guerreiro, Carlos A. M. [1] ; Cendes, Fernando [1]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Dept Neurol, Lab Neuroimagem, BR-13081970 Campinas, SP - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: Arquivos de Neuro-Psiquiatria; v. 73, n. 2, p. 79-82, FEB 2015.
Citações Web of Science: 7
Resumo

Objective: Patients with mesial temporal lobe epilepsy (MTLE) may present unstable pattern of seizures. We aimed to evaluate the occurrence of relapse-remitting seizures in MTLE with (MTLE-HS) and without (MTLE-NL) hippocampal sclerosis. Method: We evaluated 172 patients with MTLE-HS (122) or MTLE-NL (50). Relapse-remitting pattern was defined as periods longer than two years of seizure-freedom intercalated with seizure recurrence. ``Infrequent seizures{''} was considered as up to three seizures per year and ``frequent seizures{''} as any period of seizures higher than that. Results: Thirty-seven (30%) MTLE-HS and 18 (36%) MTLE-NL patients had relapse-remitting pattern (X-2, p = 0.470). This was more common in those with infrequent seizures (X-2, p < 0.001). Twelve MTLE-HS and one MTLE-NL patients had prolonged seizure remission between the first and second decade of life (X-2, p = 0.06). Conclusion: Similar proportion of MTLE-HS or MTLE-NL patients present relapse-remitting seizures and this occurs more often in those with infrequent seizures. (AU)

Processo FAPESP: 09/54552-9 - Estudo da progressão de dano na epilepsia de lobo temporal mesial com ou sem sinais de esclerose hipocampal
Beneficiário:Ana Carolina Coan
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 05/56578-4 - Centro multimodal de neuroimagens para estudos em epilepsia
Beneficiário:Fernando Cendes
Linha de fomento: Auxílio à Pesquisa - Programa CINAPCE - Temático