Tandem mass spectrometry (ICP-MS/MS) for overcoming molybdenum oxide interferences on Cd determination in milk

Autor(es)

Amais, Renata S. ^[1] ; Virgilio, Alex ^[2] ; Schiavo, Daniela ^[3] ; Nobrega, Joaquim A. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Ctr Nucl Energy Agr, BR-13416000 Piracicaba, SP - Brazil

^[2] Univ Fed Sao Carlos, Dept Chem, Grp Appl Instrumental Anal, BR-13565905 Sao Carlos, SP - Brazil

^[3] Agilent Technol Brazil, BR-06460040 Barueri, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Microchemical Journal; v. 120, p. 64-68, MAY 2015.
• Citações Web of Science: 28

Resumo

It is well known that molybdenum oxides affect Cd determination by inductively coupled plasma mass spectrometry (ICP-MS). It is proposed here a procedure for simultaneous determination of Cd and Mo. The effectiveness of the ICP-MS with tandem configuration (ICP-MS/MS) using octopole reaction system (ORS3) pressurized with oxygen gas and MS/MS mode to overcome Mo oxide-based interferences on Cd determination was evaluated. Cadmium was determined as free atom ion and Mo was determined as MoO2+ employing a 0.5 mL min(-1) oxygen gas flow rate into the ORS3. Non-fat and whole milk powder certified reference materials (NIST SRM 8435 and SRM 1549) were used for checking the accuracy of the proposed procedure. The microwave-assisted digestion was carried out using diluted nitric acid solution (2.6 mol L-1 HNO3) and hydrogen peroxide (30% m m(-1)). According to Student's t-test, reference and determined values were in agreement at a 95% confidence level, except for Cd-111 and Cd-113 in SRM 1549. (C) 2015 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 13/26857-5 - Teores totais e análise de especiação química de As, Cr e Se usando colunas monolíticas a baixa pressão e técnicas com plasma acoplado indutivamente
• Beneficiário: Renata Stábile Amais
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado