| Texto completo | |
| Autor(es): |
de Oliveira, Diogo Noin
[1]
;
Delafiori, Jeany
[1]
;
Ferreira, Monica Siqueira
[1]
;
Catharino, Rodrigo Ramos
[1]
Número total de Autores: 4
|
| Afiliação do(s) autor(es): | [1] Univ Estadual Campinas, Sch Pharmaceut Sci, Innovare Biomarkers Lab, BR-13083877 Campinas, SP - Brazil
Número total de Afiliações: 1
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES; v. 988, p. 13-19, APR 15 2015. |
| Citações Web of Science: | 1 |
| Resumo | |
Sunlight exposure causes several types of injury to humans, especially on the skin; among the most common harmful effects due to ultraviolet (UV) exposure are erythema, pigmentation and lesions in DNA, which may lead to cancer. These long-term effects are minimized with the use of sunscreens, a class of cosmetic products that contains UV filters as the main component in the formulation; such molecules can absorb, reflect or diffuse UV rays, and can be used alone or as a combination to broaden the protection on different wavelengths. Currently, worldwide regulatory agencies define which ingredients and what quantities must be used in each country, and enforce companies to conduct tests that confirm the Sun Protection Factor (SPF) and the UVA (Ultraviolet A) factor. Standard SPF determination tests are currently conducted in vivo, using human subjects. In an industrial mindset, apart from economic and ethical reasons, the introduction of an in vitro method emerges as an interesting alternative by reducing risks associated to UV exposure on tests, as well as providing assertive analytical results. The present work aims to describe a novel methodology for SPF determination directly from sunscreen formulations using the previously described cosmetomics platform and mass spectrometry as the analytical methods of choice. (C) 2015 Elsevier B.V. All rights reserved. (AU) | |
| Processo FAPESP: | 13/20066-6 - Aplicação da Cosmetômica no desenvolvimento de uma metodologia inovadora para análise de protetores solares |
| Beneficiário: | Jeany Delafiori |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 11/50400-0 - Metabolismo energético, estado redox e funcionalidade mitocondrial na morte celular e em desordens cardiometabólicas e neurodegenerativas |
| Beneficiário: | Aníbal Eugênio Vercesi |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 14/00084-2 - Identificação de adulterações e determinação simultânea de nutrientes e contaminantes em alimentos por análise direta em espectrometria de massas e imagem |
| Beneficiário: | Diogo Noin de Oliveira |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |