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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Resting Heart Rate Is Not a Good Predictor of a Clustered Cardiovascular Risk Score in Adolescents: The HELENA Study

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Autor(es):
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Ferreira de Moraes, Augusto Cesar [1, 2, 3] ; Cassenote, Alex Jones Flores [4] ; Leclercq, Catherine [5] ; Dallongeville, Jean [6] ; Androutsos, Odysseas [7] ; Toeroek, Katalin [8] ; Gonzalez-Gross, Marcela [9, 10] ; Widhalm, Kurt [11] ; Kafatos, Anthony [12] ; Carvalho, Heraclito Barbosa [1, 3] ; Alberto Moreno, Luis [2, 1]
Número total de Autores: 11
Afiliação do(s) autor(es):
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[1] Univ Sao Paulo, Sch Med, Dept Prevent Med, Sao Paulo - Brazil
[2] Univ Zaragoza, Fac Ciencias Salud, GENUD Growth Exercise Nutr & Dev Res Grp, Zaragoza - Spain
[3] Univ Sao Paulo, Sch Med, YCARE Youth Child & cARdiovasc Risk & Environm Re, Sao Paulo - Brazil
[4] Univ Sao Paulo, Sch Med, Dept Infect & Parasit Dis, Sao Paulo - Brazil
[5] Natl Inst Food & Nutr Res, Rome - Italy
[6] Inst Pasteur, F-59019 Lille - France
[7] Harokopio Univ, Dept Nutr & Dietet, Athens - Greece
[8] Univ Pecs, Fac Med, Dept Paediat, Pecs - Hungary
[9] Tech Univ Madrid, Fac Phys Act & Sport INEF, Dept Hlth & Human Performance, Madrid - Spain
[10] Univ Bonn, Rhein Friedrich Wilhelms, Inst Ernahrungs & Lebensmittelwissensch Humanemah, Dortmund - Germany
[11] Private Med Univ Salzburg, Dept Paediat, Salzburg - Austria
[12] Univ Crete Herakl, Sch Med, Prevent Med & Nutr Unit, Iraklion, NE - Greece
Número total de Afiliações: 12
Tipo de documento: Artigo Científico
Fonte: PLoS One; v. 10, n. 5 MAY 26 2015.
Citações Web of Science: 1
Resumo

Background Resting heart rate (RHR) reflects sympathetic nerve activity a significant association between RHR and all-cause and cardiovascular mortality has been reported in some epidemiologic studies. Methods To analyze the predictive power and accuracy of RHR as a screening measure for individual and clustered cardiovascular risk in adolescents. The study comprised 769 European adolescents (376 boys) participating in the HELENA cross-sectional study (2006-2008) were included in this study. Measurements on systolic blood pressure, HOMA index, triglycerides, TC/HDL-c, VO(2)max and the sum of four skinfolds were obtained, and a clustered cardiovascular disease (CVD) risk index was computed. The receiver operating characteristics curve was applied to calculate the power and accuracy of RHR to predict individual and clustered CVD risk factors. Results RHR showed low accuracy for screening CVD risk factors in both sexes (range 38.5%-54.4% in boys and 45.5%-54.3% in girls). Low specificity's (15.6%-19.7% in boys; 18.1%-20.0% in girls) were also found. Nevertheless, the sensitivities were moderate-to-high (61.4%-89.1% in boys; 72.9%-90.3% in girls). Conclusion RHR is a poor predictor of individual CVD risk factors and of clustered CVD and the estimates based on RHR are not accurate. The use of RHR as an indicator of CVD risk in adolescents may produce a biased screening of cardiovascular health in both sexes. (AU)

Processo FAPESP: 11/11137-1 - Pressão arterial elevada e agregação de fatores de risco em adolescentes: um estudo multicêntrico
Beneficiário:Augusto César Ferreira de Moraes
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 11/20662-2 - Pressão arterial elevada e agregação de fatores de risco em adolescentes: um estudo multicêntrico
Beneficiário:Augusto César Ferreira de Moraes
Linha de fomento: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
Processo FAPESP: 14/13367-2 - Desenvolvimento e aplicação de métodos para avaliar os comportamentos relacionados com o balanço energético em crianças/adolescentes em um estudo multicêntrico: SAYCARE study
Beneficiário:Augusto César Ferreira de Moraes
Linha de fomento: Bolsas no Brasil - Pós-Doutorado