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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Oral aspects in celiac disease children: clinical and dental enamel chemical evaluation

Texto completo
Autor(es):
de Carvalho, Fabricio Kitazono [1] ; de Queiroz, Alexandra Mussolino [1] ; Bezerra da Silva, Raquel Assed [1] ; Sawamura, Regina [2] ; Bachmann, Luciano [3] ; Bezerra da Silva, Lea Assed [1] ; Nelson-Filho, Paulo [1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Pediat Dent, BR-14040904 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Childcare & Pediat, BR-14040904 Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Sch Philosophy Sci & Letters Ribeirao Preto, Dept Phys, BR-14040904 Ribeirao Preto, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY; v. 119, n. 6, p. 636-643, JUN 2015.
Citações Web of Science: 12
Resumo

Objective. The aim of this study was to evaluate the oral manifestations of celiac disease (CD), the chemical composition of dental enamel, and the occurrence of CD in children with dental enamel defects (DEDs). Study Design. In the study, 52 children with CD and 52 controls were examined for DEDs, recurrent aphthous stomatitis (RAS), dental caries experience, and salivary parameters. In addition, 10 exfoliated primary enamel molars from each group were analyzed by energy dispersive x-ray spectroscopy and Fourier transform infrared spectroscopy. Fifty children with DEDs were submitted to CD diagnosis. Results. Among the children with CD, a higher prevalence of DEDs (P = .00001) and RAS (P = .0052), lower caries experience (P = .0024), and reduction of salivary flow (P = .0060) were observed. Dental enamel from the children with CD demonstrated a lower calcium-to-phosphorus ratio (P = .0136), but no difference in the carbonate-to-phosphate ratio (P = .5862) was observed. In the multivariate analysis, CD was a protective factor for caries (OR = 0.74) and a risk factor for RAS (OR3.23). Conclusions. The children with CD presented with more RAS, DEDs, reduction of salivary flow, and chemical alterations in the enamel. (AU)

Processo FAPESP: 10/20482-1 - Doença celíaca: repercussões bucais e estudo do esmalte como marcador da doença, em crianças
Beneficiário:Alexandra Mussolino de Queiroz
Linha de fomento: Auxílio à Pesquisa - Regular