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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Antimicrobial activity of the essential oil of Tetradenia riparia (Hochst.) Codd. (Lamiaceae) against cariogenic bacteria

Texto completo
Autor(es):
de Melo, Nathalya Isabel [1] ; de Carvalho, Carlos Eduardo [1] ; Fracarolli, Leticia [1] ; Cunha, Wilson Roberto [1] ; Sola Veneziani, Rodrigo Cassio [1] ; Gomes Martins, Carlos Henrique [1] ; Miller Crotti, Antonio Eduardo [2, 1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Franca, Nucleo Pesquisas Ciencias Exatas & Tecnol, Franca, SP - Brazil
[2] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Brazilian Journal of Microbiology; v. 46, n. 2, p. 519-525, APR-JUN 2015.
Citações Web of Science: 14
Resumo

In Brazilian folk medicine, Tetradenia riparia (Hochst.) Codd. (Lamiaceae) is used to treat toothaches and dental abscesses and diseases induced by worms, bacteria, or fungi. This paper aims to investigate the chemical composition and the antibacterial effects of the essential oil obtained from Tetradenia riparia leaves (TR-EO) grown in Southeastern Brazil against a representative panel of oral pathogens. We evaluated the antibacterial activity of TR-EO in terms of the minimal inhibitory concentration (MIC). We identified aromadendrene oxide (14.0%), (E, E)-farnesol (13.6%), dronabinol (12.5%), and fenchone (6.2%) as the major constituents of TR-EO. TR-EO displayed MIC values between 31.2 and 500 mu g/mL, with the lowest MIC value being obtained against Streptococcus mitis (31.2 mu g/mL), S. mutans (62.5 mu g/mL), S. sobrinus (31.2 mu g/mL), and Lactobacillus casei (62.5 mu g/mL). In time-kill experiments, TR-EO demonstrated bactericidal activity against S. mutans within the first 12 h, resulting in a curve profile similar to that of chlorhexidine. These results revealed that the essential oil of Tetradenia riparia displays promising activity against most of the selected cariogenic bacteria, including Streptococcus mutans. (AU)

Processo FAPESP: 07/54241-8 - Prospecção de óleos essenciais de espécies brasileiras cultiváveis com atividade contra patógenos da cavidade bucal
Beneficiário:Antônio Eduardo Miller Crotti
Linha de fomento: Auxílio à Pesquisa - Programa BIOTA - Apoio a Jovens Pesquisadores