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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Physical and mechanical characterization of a porous cement for metaphyseal bone repair

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Autor(es):
Cimatti, Bruno [1] ; Engel, Edgard Eduard [1] ; Nogueira-Barbosa, Marcello Henrique [2] ; Frighetto, Paulo Donato [3] ; Volpon, Jose Batista [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Biomech Med & Rehabil Locomotor Syst, Lab Bioengn, BR-14049 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Div Radiol & Diagnost Imaging, BR-14049 Ribeirao Preto, SP - Brazil
[3] Inst Fed Educ Ciencia & Tecnol, Sao Paulo, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Acta Ortopédica Brasileira; v. 23, n. 4, p. 197-201, JUL-AUG 2015.
Citações Web of Science: 5
Resumo

OBJECTIVE: Macroporous cement with mechanical properties similar to cancellous bone may improve the treatment of large bone defects in relation to solid acrylic cement. The aim of this study was to compare physical and mechanical characteristics of a polymethyl methacrylate (PMMA) based porous cement with cancellous bone. METHODS: Compressive strength and pore size, interconnectivity, and distribution of cylindrical porous PMMA cement samples containing 10% (G1), 20% (G2) or 30% (G3) effervescent components were analyzed. Results were compared to bovine cancellous bone (G4) and solid PMMA (G5) samples. RESULTS: Scanning electron microscopy (SEM) of all experimental samples (G1 - G3) revealed a random distribution and a wide size variation of pores ranging from 50 µm to 3 mm. Micro-CT showed that G2 have high porosity and lower interconnectivity of pores. No significant differences in yield strength and Young's modulus were observed among G1, G2 and G3. G4 samples were slightly stronger and less elastic than the other groups. Solid PMMA is extremely strong and inelastic. CONCLUSIONS: PMMA based porous cement met the expected characteristics. High porosity with large and interconnected pores may allow for bone ingrowth. Strength and elasticity similar to cancellous bone may enhance mechanical stimuli to bone remodeling. Observational Descriptive Study. (AU)

Processo FAPESP: 10/08315-2 - Desenvolvimento e caracterização de um cimento esponjoso para preenchimento de falhas ósseas. análise morfométrica e ensaio mecânico.
Beneficiário:Edgard Eduard Engel
Modalidade de apoio: Auxílio à Pesquisa - Regular