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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Antioxidant potential of dietary chia seed and oil (Salvia hispanica L.) in diet-induced obese rats

Texto completo
Autor(es):
Marineli, Rafaela da Silva [1] ; Lenquiste, Sabrina Alves [1] ; Moraes, Erica Aguiar [1] ; Marostica, Jr., Mario Roberto [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, UNICAMP, Fac Food Engn, Dept Food & Nutr, Sao Paulo - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: Food Research International; v. 76, n. 3, p. 666-674, OCT 2015.
Citações Web of Science: 15
Resumo

This study aimed to investigate the effects of dietary chia seed and oil on plasma and liver oxidative status in dietinduced obese rats. Thirty-six Wistar rats were divided in six groups (6 animals each): control group was fed the American Institute of Nutrition (AIN)-93 M diet; HFF group was fed a high-fat and high-fructose (HFF) diet; chia seed short (6-weeks) and long (12-weeks) treatments received an HFF diet with chia seed; chia oil short (6-weeks) and long (12-weeks) treatments received an HFF diet with chia oil. Plasma and hepatic biomarkers of lipid peroxidation, endogenous enzymatic and non-enzymatic antioxidant systems and antioxidant capacity were determined. HFF diet induced weight gain, oxidative stress and lipid peroxidation in plasma and liver of animals. Compared to HFF group chia seed and chia oil (12 and 6 weeks) intake increased plasma reduced thiol (GSH) levels, plasma catalase (CAT) and glutathione peroxidase (GPx) activities. In the liver glutathione reductase (GRd) activity was enhanced, while CAT and GPx activities did not change. There were no differences in plasma and liver superoxide dismutase activity among chia diets and HFF group. Chia (seed and oil) intake did not modify liver lipid peroxidation, but was able to reduce plasma thiobarbituric acid reactive substances (TBARS) and 8-isoprostane levels increased by HFF group. Plasma and hepatic antioxidant capacity values were increased in chia seed and oil groups about 35% and 47%, respectively, compared to HFF group. Chia groups presented similar antioxidant potential, regardless of treatment time. Dietary chia seed and oil reduced oxidative stress in vivo, since it improved antioxidant status and reduced lipid peroxidation in diet-induced obese rats. (C) 2015 Elsevier Ltd. All rights reserved. (AU)

Processo FAPESP: 12/23813-4 - Avaliação do potencial da semente e do óleo de chia (Sálvia hispanica L.) na prevenção e no tratamento da obesidade e comorbidades induzida por dieta hiperlipídica e hiperglicídica in vivo
Beneficiário:Mário Roberto Maróstica Junior
Linha de fomento: Auxílio à Pesquisa - Regular