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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Flavonoids and antioxidant potential of nine Argentinian species of Croton (Euphorbiaceae)

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Autor(es):
Furlan, Claudia M. [1] ; Santos, Katia Pereira [1] ; Sedano-Partida, Martha Dalila [1] ; da Motta, Lucimar Barbosa [2] ; Santos, Deborah Yara A. C. [1] ; Faria Salatino, Maria Luiza [1] ; Negri, Giuseppina [3] ; Berry, Paul E. [4] ; van Ee, Benjamin W. [5] ; Salatino, Antonio [1]
Número total de Autores: 10
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Biosci, Dept Bot, Rua Matao 277, BR-05508090 Sao Paulo, SP - Brazil
[2] Univ Paulista, BR-01533000 Sao Paulo, SP - Brazil
[3] Univ Fed Sao Paulo, Dept Psicobiol, Sao Paulo, SP - Brazil
[4] Univ Michigan Herbarium, Dept Ecol & Evolutionary Biol, Ann Arbor, MI 48108 - USA
[5] Recinto Univ Mayaguez, Dept Biol, Mayaguez, PR 00680 - USA
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: BRAZILIAN JOURNAL OF BOTANY; v. 38, n. 4, p. 693-702, DEC 2015.
Citações Web of Science: 10
Resumo

Croton is a large genus of Euphorbiaceae and many of its species are used medicinally. This study was performed to analyze the flavonoid composition and the antioxidant potential of hydroalcoholic extracts of nine Argentinian species of Croton: C. andinus Mull. Arg.; C. argentinus Mull. Arg.; C. catamarcensis Ahumada; C. cordobensis Ahumada; C. curiosus Croizat; C. lachnostachyus Baill.; C. lanatus Lam. var. lorentzii (Mull. Arg.) P.E. Berry; C. saltensis Griseb.; and C. serratifolius Baill. Few investigations studying the analyses of flavonoid glycosides in Croton have been carried out. The hydroalcoholic extracts (80 % methanol) from leaves were analyzed by high-performance liquid chromatography-mass spectrometry. The antioxidant activity was analyzed by the 1,1-diphenyl-2-picryl-hidrasil, Sigma (DPPH), ferric reducing antioxidant potential (FRAP), and Folin-Ciocalteu methods. O-Glycosides of flavonols (kaempferol, quercetin, and isorhamnetin) and flavones (apigenin) were ubiquitous in the analyzed samples. Rutin was frequent and predominant, especially in Adenophylli section. Acylglycosides of either quercetin or kaempferol (tiliroside) were detected in most samples. C. argentinus and C. serratifolius were the species with the highest antioxidant capacity and the highest total content in proanthocyanidins and total phenols together. Significant degree (P<0.05) of correlation was found between relative abundances of total phenols, proanthocyanidins, and quercetin derivatives, with FRAP and DPPH. Principal Component analysis showed a close affinity among Adenophylli species. (AU)

Processo FAPESP: 07/02518-6 - Química, potencial farmacológico e filogenia molecular de Croton (Euphorbiaceae), com ênfase em espécies nativas
Beneficiário:Antonio Salatino
Linha de fomento: Auxílio à Pesquisa - Regular