Structural characterization of beta-carotene-incorporated nanovesicles produced with non-purified phospholipids

Autor(es)

Michelon, Mariano ^[1] ; Mantovani, Raphaela Araujo ^[1] ; Sinigaglia-Coimbra, Rita ^[2] ; de la Torre, Lucimara Gaziola ^[3] ; Cunha, Rosiane Lopes ^[1]

Afiliação do(s) autor(es)

^[1] Univ Campinas UNICAMP, Fac Food Engn, Dept Food Engn, BR-13083862 Campinas, SP - Brazil

^[2] Fed Univ Sao Paulo UNIFESP, Paulista Sch Med, Ctr Electron Microscopy, BR-04023062 Sao Paulo, SP - Brazil

^[3] Univ Campinas UNICAMP, Fac Chem Engn, Dept Mat & Bioproc Engn, BR-13083852 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Food Research International; v. 79, p. 95-105, JAN 2016.
• Citações Web of Science: 15

Resumo

The technical feasibility of obtaining beta-carotene-incorporated phospholipid nanovesicles using non-purified soybean lecithins was studied. For this purpose, three lecithin-types were evaluated. Nanovesicles were characterized by average hydrodynamic diameter, particle size distribution, polydispersity index, zeta-potential, transmission electron microscopy, membrane microviscosity, small angle X-ray scattering and capacity of lipid peroxidation inhibition. In general, the beta-carotene incorporation did not promote a significant increase on average hydrodynamic diameter, but vesicles produced from lecithins containing triglycerides showed lower polydispersity. The lecithin type used to produce nanovesicles did not influence the beta-carotene loading capacity, but significantly influenced the microviscosity of liposomal membrane and lipid peroxidation inhibition capacity. Non-enzymatically modified lecithin (containing or not triglycerides) showed similar efficiency and peroxidation inhibition capacity considering beta-carotene incorporation. Therefore, low-cost non-purified lecithin can be employed for production of liposomal systems as an encapsulating and/or delivery system to be used in food products. (C) 2015 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 09/54137-1 - EMUS: aquisição de um analisador de distribuição de tamanho de partículas, um medidor de potencial zeta, um spray dryer e um sistema de cromatografia líquida de ultra alta pressão / espectrômetro de massa
• Beneficiário: Miriam Dupas Hubinger
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários
• Processo FAPESP: 07/54520-4 - Estudo do processo de hidrolise enzimatica de carne de frango, microencapsulacao e secagem por spray dryer.
• Beneficiário: Miriam Dupas Hubinger
• Modalidade de apoio: Auxílio à Pesquisa - Regular