The Xanthomonas type IV pilus

Autor(es)

Dunger, German ^{[1, 2]} ; Llontop, Edgar ^[1] ; Guzzo, Cristiane R. ^[3] ; Farah, Chuck S. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Quim, Dept Bioquim, Ave Prof Lineu Prestes 748, BR-05508000 Sao Paulo, SP - Brazil

^[2] Univ Nacl Litoral, Fac Ciencias Agr, Dept Prod Anim, Kreder 2805, 3080HOF, Esperanza, Santa Fe - Argentina

^[3] Univ Sao Paulo, Inst Ciencias Biomed, Dept Microbiol, Ave Prof Lineu Prestes 1374, BR-05508900 Sao Paulo, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: Current Opinion in Microbiology; v. 30, p. 88-97, APR 2016.
• Citações Web of Science: 10

Resumo

Type IV pill, a special class of bacterial surface filaments, are key behavioral mediators for many important human pathogens. However, we know very little about the role of these structures in the lifestyles of plant-associated bacteria. Over the past few years, several groups studying the extensive genus of Xanthomonas spp. have gained insights into the roles of played by type IV pili in bacteria host interactions and pathogenesis, motility, biofilm formation, and interactions with bacteriophages. Protein-protein interaction studies have identified T4P regulators and these, along with structural studies, have begun to reveal some of the possible molecular mechanisms that may control the extension/retraction cycles of these dynamic filaments. (AU)

• Processo FAPESP: 11/07777-5 - Sinalização por c-di-GMP e o sistema de secreção de macromoléculas do tipo IV em Xanthomonas citri
• Beneficiário: Shaker Chuck Farah
• Modalidade de apoio: Auxílio à Pesquisa - Temático