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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Visceral leishmaniasis in the state of Sao Paulo, Brazil: spatial and space-time analysis

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Autor(es):
Mozini Cardim, Marisa Furtado ; Guirado, Marluci Monteiro ; Dibo, Margareth Regina ; Chiaravalloti Neto, Francisco
Número total de Autores: 4
Tipo de documento: Artigo Científico
Fonte: Revista de Saúde Pública; v. 50, 2016.
Citações Web of Science: 10
Resumo

OBJECTIVE: To perform both space and space-time evaluations of visceral leishmaniasis in humans in the state of Sao Paulo, Brazil. METHODS: The population considered in the study comprised autochthonous cases of visceral leishmaniasis and deaths resulting from it in Sao Paulo, between 1999 and 2013. The analysis considered the western region of the state as its studied area. Thematic maps were created to show visceral leishmaniasis dissemination in humans in the municipality. Spatial analysis tools Kernel and Kernel ratio were used to respectively obtain the distribution of cases and deaths and the distribution of incidence and mortality. Scan statistics were used in order to identify spatial and space-time clusters of cases and deaths. RESULTS: The visceral leishmaniasis cases in humans, during the studied period, were observed to occur in the western portion of Sao Paulo, and their territorial extension mainly followed the eastbound course of the Marechal Rondon highway. The incidences were characterized as two sequences of concentric ellipses of decreasing intensities. The first and more intense one was found to have its epicenter in the municipality of Castilho (where the Marechal Rondon highway crosses the border of the state of Mato Grosso do Sul) and the second one in Bauru. Mortality was found to have a similar behavior to incidence. The spatial and space-time clusters of cases were observed to coincide with the two areas of highest incidence. Both the space-time clusters identified, even without coinciding in time, were started three years after the human cases were detected and had the same duration, that is, six years. CONCLUSIONS: The expansion of visceral leishmaniasis in Sao Paulo has been taking place in an eastbound direction, focusing on the role of highways, especially Marechal Rondon, in this process. The space-time analysis detected the disease occurred in cycles, in different spaces and time periods. These meetings, if considered, may contribute to the adoption of actions that aim to prevent the disease from spreading throughout the whole territory of Sao Paulo or to at least reducing its expansion speed. (AU)

Processo FAPESP: 10/20279-1 - Análise espacial da ocorrência de leishmaniose visceral americana no estado de São Paulo, Brasil
Beneficiário:Francisco Chiaravalloti Neto
Linha de fomento: Auxílio à Pesquisa - Regular