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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Pediococcus spp.: An important genus of lactic acid bacteria and pediocin producers

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Autor(es):
Porto, Maria Carolina W. ; Kuniyoshi, Tais Mayumi ; Azevedo, P. O. S. ; Vitolo, Michele ; Oliveira, R. P. S.
Número total de Autores: 5
Tipo de documento: Artigo de Revisão
Fonte: BIOTECHNOLOGY ADVANCES; v. 35, n. 3, p. 361-374, MAY-JUN 2017.
Citações Web of Science: 28
Resumo

Probiotics have gained increasing attention due to several health benefits related to the human digestive and immune systems. Pediococcus spp. are lactic acid bacteria (LAB) that are widely described as probiotics and characterized as coccus-shaped bacteria (arranged in tetrads), Gram-positive, non-motile, non-spore forming, catalase-negative, and facultative anaerobes. There are many Pediococcus strains that produce pediocin, an effective antilisterial bacteriocin. Pediocins are small, cationic molecules consisting of a conserved hydrophilic N-terminal portion containing the YGNGV motif and an amphiphilic or hydrophobic C-terminal variable portion. A number of studies have been developed with Pediococcus isolated from multiple biological niches to conduct fermentation processes for pediocin or Pediococcus cell production. This review gathers the most significant information about the cultivation, mode of action, and variability of bacteriocins produced by Pediococcus spp., emphasizing their applications in the areas of food and clinical practice. This updated panorama assists in delimiting the challenges that still need to be overcome for pediocin use to be approved for human consumption and the food industry. (C) 2017 Elsevier Inc. All rights reserved. (AU)

Processo FAPESP: 16/06284-9 - Produção biotecnológica de pediocina: otimização do rendimento e efeitos biológicos sobre células do sistema imune
Beneficiário:Ricardo Pinheiro de Souza Oliveira
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 15/24777-0 - Otimização da produção de pediocina A por Pediococcus pentosaceus ATCC 43200
Beneficiário:Taís Mayumi Kuniyoshi
Linha de fomento: Bolsas no Brasil - Pós-Doutorado