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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The Preventive Control of Zoonotic Visceral Leishmaniasis: Efficacy and Economic Evaluation

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Autor(es):
Shimozako, Helio Junji ; Wu, Jianhong ; Massad, Eduardo
Número total de Autores: 3
Tipo de documento: Artigo Científico
Fonte: COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE; 2017.
Citações Web of Science: 2
Resumo

Zoonotic Visceral Leishmaniasis (ZVL) is one of the world's deadliest and neglected infectious diseases, according to World Health Organization. This disease is one of major human and veterinary medical significance. The sandfly and the reservoir in urban areas remain among the major challenges for the control activities. In this paper, we evaluated five control strategies (positive dog elimination, insecticide impregnated dog collar, dog vaccination, dog treatment, and sandfly population control), considering disease control results and cost-effectiveness. We elaborated a mathematical model based on a set of differential equations in which three populations were represented (human, dog, and sandfly). Humans and dogs were divided into susceptible, latent, clinically ill, and recovery categories. Sandflies were divided into noninfected, infected, and infective. As the main conclusions, the insecticide impregnated dog collar was the strategy that presented the best combination between disease control and cost-effectiveness. But, depending on the population target, the control results and cost-effectiveness of each strategy may differ. More and detailed studies are needed, specially one which optimizes the control considering more than one strategy in activity. (AU)

Processo FAPESP: 11/02633-5 - Modelo de otimização para o controle da leishmaniose: análise epidemiológica e econômica
Beneficiário:Hélio Junji Shimozako
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 13/13347-9 - Impacto da otimização do controle da leishmaniose visceral: relação entre investimento e eficácia
Beneficiário:Hélio Junji Shimozako
Linha de fomento: Bolsas no Exterior - Estágio de Pesquisa - Doutorado