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(Referência obtida automaticamente do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Noninvasive intracranial pressure monitoring for HIV-associated cryptococcal meningitis

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Bollela, V. R. ; Frigieri, G. ; Vilar, F. C. ; Spavieri, Jr., D. L. ; Tallarico, F. J. ; Tallarico, G. M. ; Andrade, R. A. P. ; de Haes, T. M. ; Takayanagui, O. M. ; Catai, A. M. ; Mascarenhas, S.
Número total de Autores: 11
Tipo de documento: Artigo Científico
Fonte: Brazilian Journal of Medical and Biological Research; v. 50, n. 9, p. -, 2017.
Citações Web of Science: 0
Resumo

Mortality and adverse neurologic sequelae from HIV-associated cryptococcal meningitis (HIV-CM) remains high due to raised intracranial pressure (ICP) complications. Cerebrospinal fluid (CSF) high opening pressure occurs in more than 50% of HIV-CM patients. Repeated lumbar puncture with CSF drainage and external lumbar drainage might be required in the management of these patients. Usually, there is a high grade of uncertainty and the basis for clinical decisions regarding ICP hypertension tends to be from clinical findings (headache, nausea and vomiting), a low Glasgow coma scale score, and/or fundoscopic papilledema. Significant neurological decline can occur if elevated CSF pressures are inadequately managed. Various treatment strategies to address intracranial hypertension in this setting have been described, including: medical management, serial lumbar punctures, external lumbar and ventricular drain placement, and either ventricular or lumbar shunting. This study aims to evaluate the role of a non-invasive intracranial pressure (ICP-NI) monitoring in a critically ill HIV-CM patient. (AU)

Processo FAPESP: 14/50618-3 - Desenvolvimento de sensor indutivo minimamente invasivo para monitorar a pressão intracraniana
Beneficiário:Sergio Mascarenhas Oliveira
Linha de fomento: Auxílio à Pesquisa - Pesquisa Inovativa em Pequenas Empresas - PIPE