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(Referência obtida automaticamente do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Algorithm for predicting macular dysfunction based on moment invariants classification of the foveal avascular zone in functional retinal images

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Autor(es):
Angélica Moises Arthur ; Rangel Arthur ; Alexandre Gonçalves Silva ; Marina Silva Fouto ; Yuzo Iano ; Jacqueline Mendonça Lopes de Faria
Número total de Autores: 6
Tipo de documento: Artigo Científico
Fonte: Res. Biomed. Eng.; v. 33, n. 4, p. -, Out. 2017.
Resumo

Abstract Introduction A new method for segmenting and quantifying the macular area based on morphological alternating sequential filtering (ASF) is proposed. Previous studies show that persons with diabetes present alterations in the foveal avascular zone (FAZ) prior to the appearance of retinopathy. Thus, a proper characterization of FAZ using a method of automatic classification and prediction is a supportive and complementary tool for medical evaluation of the macular region, and may be useful for possible early treatment of eye diseases in persons without diabetic retinopathy. Methods We obtained high-resolution retinal images using a non-invasive functional imaging system called Retinal Function Imager to generate a series of combined capillary perfusion maps. We filtered sequentially the macular images to reduce the complexity by ASF. Then we segmented the FAZ using watershed transform from an automatic selection of markers. Using Hu’s moment invariants as a descriptor, we can automatically classify and categorize each FAZ. Results The FAZ differences between non-diabetic volunteers and diabetic subjects were automatically distinguished by the proposed system with an accuracy of 81%. Conclusion This is an innovative method to classify FAZ using a fully automatic algorithm for segmentation (based on morphological operators) and for the classification (based on descriptor formed by Hu’s moments) despite the presence of edema or other structures. This is an alternative tool for eye exams, which may contribute to the analysis and evaluation of FAZ morphology, promoting the prevention of macular impairment in diabetics without retinopathy. (AU)

Processo FAPESP: 14/22687-0 - Contribuição da via AMPK para a fibrose renal e patogênese da nefro e retinopatia diabéticas
Beneficiário:Jose Butori Lopes de Faria
Linha de fomento: Auxílio à Pesquisa - Temático
Processo FAPESP: 09/52890-4 - Avaliação in vivo dos possíveis efeitos agudos de agentes antioxididantes na microcirculação da retina de pacientes diabéticos através de uma nova tecnologia computacional oftalmológica não invasiva: possíveis efeitos da ingestão do cacau e do chá verde na microcirculação retiniana
Beneficiário:Jacqueline Mendonça Lopes de Faria
Linha de fomento: Auxílio à Pesquisa - Regular