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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Zika virus infection in a pediatric patient with acute gastrointestinal involvement

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Autor(es):
Slavov, Svetoslav [1, 2] ; Matsuno, Alessandra [3] ; Yamamoto, Aparecida [3] ; Otaguiri, Katia [2, 4] ; Cervi, Maria [3] ; Covas, Dimas [1, 2] ; Kashima, Simone [2, 4]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Dept Internal Med, Fac Med Ribeirao Preto, Sao Paulo - Brazil
[2] Univ Sao Paulo, Blood Ctr Ribeirao Preto, Fac Med Ribeirao Preto, Sao Paulo - Brazil
[3] Univ Sao Paulo, Dept Pediat, Fac Med Ribeirao Preto, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Clin Toxicol & Bromatol Anal, Fac Pharmaceut Sci Ribeirao Preto, Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: PEDIATRIC REPORTS; v. 9, n. 4, p. 78-80, 2017.
Citações Web of Science: 0
Resumo

Zika virus (ZIKV) is a mosquito-borne flavivirus, which has been related to severe neurological complications in neonates. However, many clinical aspects of the infection remain unclear, especially in pediatric patients. In this case report we describe the uncommon presentation of ZIKV infection in a pediatric patient with acute gastrointestinal involvement hospitalized in a Brazilian Emergency Unit. Dengue hemorrhagic fever was initially suspected, however, the molecular result for Dengue was negative. Molecular testing for other arboviruses (ZIKV and Chikungunya), revealed positive for ZIKV RNA result in both blood and saliva. The ZIKV load in saliva (6.947 copies/mL) was higher than the vetected ZIKV RNA in plasma (1.945 copies/mL). Additionally, the performed abdominal ultrasound revealed mesenteric lymphadenitis without abdominal retention of fluids. The presentation of this case demonstrates that ZIKV can be involved in a broader range of clinical conditions than currently assumed, including pediatric emergencies, especially in regions with extensive ZIKV outbreaks. (AU)

Processo FAPESP: 09/16623-1 - Mecanismos moleculares e consequências clínicas da infecção causada pelo parvovírus B19 e citomegalovírus humanos em pacientes com hemoglobinopatias e hemofilia
Beneficiário:Svetoslav Nanev Slavov
Linha de fomento: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 13/08135-2 - CTC - Centro de Terapia Celular
Beneficiário:Dimas Tadeu Covas
Linha de fomento: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs