Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Female prostate: historical, developmental, and morphological perspectives

Texto completo
Autor(es):
Biancardi, Manoel F. [1] ; dos Santos, Fernanda C. A. [1] ; de Carvalho, Hernandes F. [2] ; Sanches, Bruno D. A. [2] ; Taboga, Sebastiao R. [3]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Fed Goias, Dept Histol Embryol & Cell Biol, Av Esperanca, Campus Samambaia, BR-74690900 Goiania, Go - Brazil
[2] Univ Estadual Campinas, Dept Struct & Funct Biol, Av Bertrand Russel, BR-13084864 Campinas, SP - Brazil
[3] State Univ Sao Paulo, Dept Biol, R Cristovao Colombo 2265, BR-15054000 Sao Jose Do Rio Preto, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo de Revisão
Fonte: Cell Biology International; v. 41, n. 11, SI, p. 1174-1183, NOV 2017.
Citações Web of Science: 10
Resumo

The female prostate was first described by Reijnier de Graaf in 1672, and even after several years this gland is still a matter of controversy. Part of this is because the biological function of this female gland is unclear. Moreover, when compared with the male prostate, the existence of this organ in females does not make sense, mainly when we consider that the major function of this gland is to produce a secretion that is responsible for guarantee the sperm survival and assure the reproductive success. However, even under a controversy field, we now have a lot of scientific information which enhances our knowledge of several important biological aspects of this gland. It is clear that this gland is found in some female mammals including humans, rodents, rabbits, bats, and dogs. Several studies with rodents showed that the female prostate is homolog of the male prostate, showing strong macroscopic and microscopic similarities with the ventral lobe of males. Besides these aspects, there are several studies reporting that diseases such as cysts, hyperplasia, and carcinoma may affect the female prostate. Therefore, although diseases involving the female prostate are rare, the susceptibility of this organ to develop lesions must be considered, especially in our recent years in which the exposure to endocrine-disrupting chemicals has greatly increased. Finally, further studies will be necessary to enhance our understanding about this gland, mainly of the developmental, evolutionary, and biological functions. (AU)

Processo FAPESP: 15/03599-6 - Avaliação do papel da via de sinalização do TGF-² na indução prostática: do seio urogenital aos primórdios do lobo ventral da próstata em camundongos e caracterização de transições similares em células RWPE1
Beneficiário:Manoel Francisco Biancardi
Linha de fomento: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 09/16789-7 - Efeitos da exposição intra-uterina e puberal do cipionato de testosterona sobre a próstata de machos e fêmeas de gerbilos senis
Beneficiário:Manoel Francisco Biancardi
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 09/53990-2 - EMU: aquisição de microscópio de varredura confocal a laser para um centro multiusuário de microscopia da UNESP
Beneficiário:Sebastião Roberto Taboga
Linha de fomento: Auxílio à Pesquisa - Programa Equipamentos Multiusuários