Enantioselective biodegradation of the pyrethroid (+/-)-lambda-cyhalothrin by marine-derived fungi

Autor(es)

Birolli, Willian G. ^[1] ; Vacondio, Bruna ^[2] ; Alvarenga, Natalia ^[1] ; Seleghim, Mirna H. R. ^[2] ; Porto, Andre L. M. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Quim Sao Carlos, Lab Quim Organ & Biocatalise, Av Joao Dagnone 1100, BR-13563120 Sao Carlos, SP - Brazil

^[2] Univ Fed Sao Carlos, UFSCAR, Ctr Ciencias Biol & Saude, Dept Ecol & Biol Evolut, Via Washington Luis, Km 235, BR-13565905 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Chemosphere; v. 197, p. 651-660, APR 2018.
• Citações Web of Science: 4

Resumo

The contamination of agricultural lands by pesticides is a serious environmental issue. Consequently, the development of bioremediation methods for different active ingredients, such as pyrethroids, is essential. In this study, the enantioselective biodegradation of (+/-)-lambda-cyhalothrin ((+/-)-LC) by marine-derived fungi was studied. Experiments were performed with different fungi strains (Aspergillus sp. CBMAI 1829, Acremonium sp. CBMAI 1676, Microsphaeropsis sp. CBMA1 1675 and Westerdykella sp. CBMAI 1679) in 3% malt liquid medium with 100 mg L-1 of (+/-)-LC. All strains biodegraded this insecticide and the residual concentrations of (+/-)-LC (79.2-55.2 mg L-1, i.e., 20.8-44.8% biodegradation), their enantiomeric excesses (2-42% ee) and the 3-phenoxybenzoic acid (PBAc) concentrations (0.0-4.1 mg L-1) were determined. In experiments for 28 days of biodegradation in the absence and presence of artificial seawater (ASW) with the most efficient strain Aspergillus sp. CBMAI 1829, increasing concentrations of PBAc with (0.0-4.8 mg L-1) and without ASW (0.0-15.3 mg L-1) were observed. In addition, a partial biodegradation pathway was proposed. All the evaluated strains biodegraded preferentially the (1R,3R,alpha S)-gamma-cyhalothrin enantiomer. Therefore, marine-derived fungi enantioselectively biodegraded (+/-)-LC and can be applied in future studies for bioremediation of contaminated areas. This enantioselective biodegradation indicates that the employment of the most active enantiomer GC as insecticide not only enable the use of a lower amount of pesticide, but also a more easily biodegradable product, reducing the possibility of environmental contamination. (C) 2018 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 04/09498-2 - Caracterização estrutural, identificação e quantificação de substâncias orgânicas e moléculas bioativas por cromatografia em fase líquida acoplada a espectrometria de massas tandem (LC-MS/MS) com equipamento híbrido quadrupolo-tempo de voo
• Beneficiário: Fernando Mauro Lanças
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários
• Processo FAPESP: 12/19934-0 - Biodegradação de pesticidas por micro-organismos (fungos e bactérias)
• Beneficiário: Andre Luiz Meleiro Porto
• Modalidade de apoio: Auxílio à Pesquisa - Regular