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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Sensitivity and specificity of a briefer version of the Cambridge Cognitive Examination (CAMCog-Short) in the detection of cognitive decline in the elderly: An exploratory study

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Autor(es):
Radanovic, Marcia [1] ; Facco, Giuliana [1] ; Forlenza, Orestes V. [1]
Número total de Autores: 3
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Hosp Clin HCFMUSP, Dept & Inst Psiquiatria, Fac Med, Lab Neurociencias LIM 27, Sao Paulo, SP - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY; v. 33, n. 5, p. 769-778, MAY 2018.
Citações Web of Science: 0
Resumo

ObjectiveTo create a reduced and briefer version of the widely used Cambridge Cognitive Examination (CAMCog) battery as a concise cognitive test to be used in primary and secondary levels of health care to detect cognitive decline. Our aim was to reduce the administration time of the original test while maintaining its diagnostic accuracy. MethodsOn the basis of the analysis of 835 CAMCog tests performed by 429 subjects (107 controls, 192 mild cognitive impairment {[}MCI], and 130 dementia patients), we extracted items that most contributed to intergroup differentiation, according to 2 educational levels (8 and >8y of formal schooling). ResultsThe final 33-item low education and 24-itemhigh education CAMCog-Short correspond to 48.5% and 35% of the original version and yielded similar rates of accuracy: area under ROC curves (AUC)>0.9 in the differentiation between controlsxdementia and MCIxdementia (sensitivities>75%; specificities>90%); AUC>0.7 for the differentiation between controls and MCI (sensitivities>65%; specificities>75%). ConclusionsThe CAMCog-Short emerges as a promising tool for a brief, yet sufficiently accurate, screening tool for use in clinical settings. Further prospective studies designed to validate its diagnostic accuracy are needed. (AU)

Processo FAPESP: 09/52825-8 - Neurobiologia da doença de Alzheimer: marcadores de risco, prognóstico e resposta terapêutica
Beneficiário:Wagner Farid Gattaz
Linha de fomento: Auxílio à Pesquisa - Temático
Processo FAPESP: 13/20695-3 - Efeito de inibidor da colinesterase no metabolismo da APP em plaquetas
Beneficiário:Tamires Alves Sarno
Linha de fomento: Bolsas no Brasil - Mestrado