Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Chronic obstructive pulmonary disease severity and its association with obstructive sleep apnea syndrome: impact on cardiac autonomic modulation and functional capacity

Texto completo
Autor(es):
Lopes Zangrando, Katiany Thays [1] ; Trimer, Renata [2] ; Soares de Carvalho, Jr., Luiz Carlos [1] ; Tinoco Areas, Guilherme Peixoto [1] ; Rossi Caruso, Flavia Cristina [1] ; Cabiddu, Ramona [1] ; Roscani, Meliza Goi [3] ; Galhardo Rizzatti, Fabiola Paula [3] ; Borghi-Silva, Audrey [1]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Univ Fed Sao Carlos, Physiotherapy Dept, Cardiopulm Physiotherapy Lab, Sao Carlos, SP - Brazil
[2] Univ Santa Cruz do Sul, Phys Educ & Hlth Dept, Santa Cruz Do Sul, RS - Brazil
[3] Univ Fed Sao Carlos, Med Dept, Sao Carlos, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE; v. 13, p. 1343-1351, 2018.
Citações Web of Science: 3
Resumo

Background: The study was conducted to determine the impact of chronic obstructive pulmonary disease (COPD) in association with obstructive sleep apnea syndrome (OSAS) on cardiac autonomic control and functional capacity. Subjects and methods: The study was a cross-sectional prospective controlled clinical study. Heart rate variability indices of 24 COPD (n = 12) and COPD+OSAS (n = 12) patients were evaluated and compared by electrocardiographic recordings acquired during rest, active postural maneuver (APM), respiratory sinus arrhythmia maneuver (RSA-m), and the 6-minute walk test (6MWT). Results: The COPD group presented higher parasympathetic modulation during APM when compared to the COPD+OSAS group (P = 0.02). The COPD+OSAS group presented higher sympathetic modulation during RSA-m when compared to the COPD group (P = 0.00). The performance during 6MWT was similarly impaired in both groups, despite the greater severity of the COPD group. Conclusion: Subjects with COPD+OSAS present marked sympathetic modulation, and the presence of OSAS in COPD subjects has a negative impact on functional capacity regardless of the severity of lung disease. (AU)

Processo FAPESP: 15/26501-1 - Estudo dos fatores limitantes ao exercício físico e efeitos dos recursos adjuntos a reabilitação nas doenças cardiorrespiratórias crônicas: uma abordagem multicêntrica
Beneficiário:Audrey Borghi e Silva
Linha de fomento: Auxílio à Pesquisa - Temático