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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review

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Autor(es):
Pascoli, Monica [1] ; de Lima, Renata [2] ; Fraceto, Leonardo F. [1]
Número total de Autores: 3
Afiliação do(s) autor(es):
[1] Sao Paulo State Univ UNESP, Environm Chem, Inst Sci & Technol, Sorocaba - Brazil
[2] Univ Sorocaba, Dept Biotechnol, Sorocaba - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo de Revisão
Fonte: FRONTIERS IN CHEMISTRY; v. 6, JAN 25 2018.
Citações Web of Science: 10
Resumo

Zein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture. (AU)

Processo FAPESP: 15/17120-4 - Avaliação da toxicidade e atividade biológica de nanopartículas de zeína contendo o biocida azadiractina
Beneficiário:Mônica Pascoli
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 15/15617-9 - Repelentes botânicos e nanotecnologia: desenvolvimento de sistemas para controle de pragas em agricultura
Beneficiário:Leonardo Fernandes Fraceto
Linha de fomento: Auxílio à Pesquisa - Regular