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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Making the invisible visible: searching for human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in Brazilian patients with viral hepatitis B and C

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Autor(es):
Caterino-de-Araujo, Adele [1] ; Alves, Fabiana Aparecida [1] ; Campos, Karoline Rodrigues [1] ; Lemos, Marcilio Figueiredo [2] ; Moreira, Regina Celia [2]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Secretaria Estado Saude Sao Paulo, Coordenadoria Controle Doencas, Inst Adolfo Lutz, Ctr Imunol, Lab Pesquisa HTLV, Sao Paulo, SP - Brazil
[2] Secretaria Estado Saude Sao Paulo, Coordenadoria Controle Doencas, Inst Adolfo Lutz, Lab Hepatites, Ctr Virol, Nucleo Doencas Transmissao Sanguinea &, Sao Paulo, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Memórias do Instituto Oswaldo Cruz; v. 113, n. 2, p. 130-134, FEB 2018.
Citações Web of Science: 2
Resumo

With this study, the authors hope to alert clinicians regarding the presence of human T-cell lymphotropic virus type 1 and 2 (HTLV-1/-2) infections in patients with viral hepatitis B and C in Brazil. HTLV-1/-2 were detected in 1.3% of hepatitis B virus (HBV)- and 5.3% of hepatitis C virus (HCV)-infected blood samples sent for laboratory viral load measurements. A partial association of human immunodeficiency virus (HIV)-1 and HTLV-1/-2 infection was detected in patients with HCV (HIV+, 27.3%), whereas this association was almost 100% in HBV-infected patients (HIV+, all except one). The high prevalence of HTLV-1/-2 infection among patients with hepatitis C was of concern, as HTLV-1/-2 could change the natural course of subsequent liver disease. The authors suggest including HTLV-1/-2 serology in the battery of tests used when following patients with viral hepatitis in Brazil, regardless of the HIV status. (AU)

Processo FAPESP: 12/51220-8 - Vigilância e diagnóstico de infecção por HTLV-1 e HTLV-2 em indivíduos infectados pelo HIV (vidiHIV/HTLV)
Beneficiário:Adele Caterino de Araújo
Linha de fomento: Auxílio à Pesquisa - Pesquisa em Políticas Públicas para o SUS