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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases

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Autor(es):
Gomes, Monica Fernandes [1] ; Bernardo Sichi, Luigi Giovanni [1] ; Giannasi, Lilian Chrystiane [1, 2, 3] ; Oliveira Amorim, Jose Benedito [1] ; da Rocha, Joao Carlos [1] ; Koga-Ito, Cristiane Yumi [1] ; Castillo Salgado, Miguel Angel [1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Sao Paulo State Univ UNESP, Ctr Biosci Appl Patients Special Hlth Care Needs, Inst Sci & Technol, Sao Jose dos Campos Campus, Sao Paulo, SP - Brazil
[2] Metropolitan Univ Santos UNIMES, Dent Sch, Santos, SP - Brazil
[3] Univ Ctr Anapolis UniEvangelica, Sleep Disorders Lab, Anapolis, Go - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: CASE REPORTS IN DENTISTRY; 2018.
Citações Web of Science: 1
Resumo

Ectodermal dysplasia (ED) is a rare hereditary disorder affecting the development of ectoderm-derived organs and tissues. The aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED, correlating their data with the literature. Additionally, to investigate the salivary gland disorders and their impacts on oral microbiota, we performed salivary tests, including salivary flow rate, salivary buffering capacity, and concentration levels of mutans streptococci, lactobacilli, and yeasts. All patients presented oligodontia, resulting in a significant masticatory dysfunction and aesthetic impairment. The counts of mutans streptococci (n = 3) and yeasts (n = 2) were high; on the other hand, the count of lactobacilli (n = 3) was low. Therefore, salivary and microbiological tests showed that the patients with ED, particularly the hypohidrotic type, presented a high risk of enamel caries and susceptibility to oral infections, which may be likely triggered by reduction of salivary flow and/or possible immunological disorders. (AU)

Processo FAPESP: 17/06835-8 - Avaliação da função dos músculos mastigatórios e variáveis fisiológicas do sono após terapias de bioestimulação eletro-mecânica e de uso de aparelho intraoral em pacientes com síndrome de Down: eletromiografia, polissonografia e parâmetros salivares
Beneficiário:Mônica Fernandes Gomes
Linha de fomento: Auxílio à Pesquisa - Regular