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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review

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Autor(es):
Moura, Carolina Soares [1] ; Barboza Lollo, Pablo Christiano [2] ; Morato, Priscila Neder [2] ; Amaya-Farfan, Jaime [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Fac Food Engn, Dept Food & Nutr, Prot Resources Lab, BR-13083862 Campinas, SP - Brazil
[2] Fed Univ Grande Dourados, Sch Hlth Sci, BR-79825070 Dourados, MS - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo de Revisão
Fonte: NUTRIENTS; v. 10, n. 6 JUN 2018.
Citações Web of Science: 8
Resumo

Interest in the heat shock proteins (HSPs), as a natural physiological toolkit of living organisms, has ranged from their chaperone function in nascent proteins to the remedial role following cell stress. As part of the defence system, HSPs guarantee cell tolerance against a variety of stressors, including exercise, oxidative stress, hyper and hypothermia, hyper and hypoxia and improper diets. For the past couple of decades, research on functional foods has revealed a number of substances likely to trigger cell protection through mechanisms that involve the induction of HSP expression. This review will summarize the occurrence of the most easily inducible HSPs and describe the effects of dietary proteins, peptides, amino acids, probiotics, high-fat diets and other food-derived substances reported to induce HSP response in animals and humans studies. Future research may clarify the mechanisms and explore the usefulness of this natural alternative of defense and the modulating mechanism of each substance. (AU)

Processo FAPESP: 16/06630-4 - Efeito do consumo das proteínas do soro do leite sobre as heat shock proteins (HSPs) em animais obesos induzidos por dieta cafeteria
Beneficiário:Carolina Soares de Moura
Linha de fomento: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 17/16886-9 - Impacto do consumo das proteínas do soro do leite na expressão das heat-shock proteins (HSPs) e na microbiota intestinal
Beneficiário:Jaime Amaya Farfan
Linha de fomento: Auxílio à Pesquisa - Regular