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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The combination of dynapenia and abdominal obesity as a risk factor for worse trajectories of IADL disability among older adults

Texto completo
Autor(es):
Alexandre, Tiago da Silva [1, 2] ; Scholes, Shaun [1] ; Ferreira Santos, Jair Licio [3] ; de Oliveira Duarte, Yeda Aparecida [4] ; de Oliveira, Cesar [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] UCL, Dept Epidemiol & Publ Hlth, London - England
[2] Univ Fed Sao Carlos, Dept Gerontol, Rodovia Washington Luis, Km 235, SP-310, BR-13565905 Sao Carlos, SP - Brazil
[3] Univ Sao Paulo, Dept Social Med, Ribeirao Preto - Brazil
[4] Univ Sao Paulo, Dept Med Surg Nursing, Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: Clinical Nutrition; v. 37, n. 6, A, p. 2045-2053, DEC 2018.
Citações Web of Science: 3
Resumo

Background/Objectives: The concept of dynapenic obesity has been gaining great attention recently. However, there is little epidemiological evidence demonstrating that dynapenic abdominal obese individuals have worse trajectories of disability than those with dynapenia and abdominal obesity alone. Our aim was to investigate whether dynapenia combined with abdominal obesity can result in worse trajectories of instrumental activities of daily living (IADL) among English and Brazilian older adults over eight and ten years of follow-up, respectively. Methods: We used longitudinal data from 3374 participants from the English Longitudinal Study of Ageing (ELSA) and 1040 participants from the Brazilian Health, Well-being and Aging Study (SABE) who were free from disability as assessed by IADL at baseline. IADL disability was defined herein as a difficulty to perform the following: preparing meals, managing money, using transportation, shopping, using the telephone, house cleaning, washing clothes, and taking medications according to the Lawton IADL modified scale. The study population in each country was categorized into non-dynapenic/non-abdominal obese (reference group), abdominal obese, dynapenic and dynapenic abdominal obese according to their handgrip strength (<26 kg for men and <16 kg for women) and waist circumference (>102 cm for men and >88 cm for women). We used generalized linear mixed models with IADL as the outcome. Results: The estimated change over time in IADL disability was significantly higher for participants with dynapenic abdominal obesity compared to those with neither condition in both cohorts (ELSA: +0.023, 95% CI = 0.012-0.034, p < 0.001; SABE: +0.065, 95% Cl = 0.038-0.091, p < 0.001). Abdominal obesity was also associated with changes over time in IADL disability (ELSA: +0.009, 95% Cl = 0.002-0.015, p < 0.05; SABE: +0.021, 95% CI = 0.002-0.041, p < 0.05), which was not observed for dynapenia. Conclusions: Abdominal obesity is an important risk factor for IADL decline but participants with dynapenic abdominal obesity had the highest rates of IADL decline over time among English and Brazilian older adults. (C) 2017 The Authors. Published by Elsevier Ltd. (AU)

Processo FAPESP: 15/20294-4 - Efeito aditivo da dinapenia e obesidade (obesidade dinapênica) sobre a incidência de incapacidade e óbito em idosos: uma análise comparativa entre Brasil e Inglaterra
Beneficiário:Tiago da Silva Alexandre
Linha de fomento: Bolsas no Exterior - Pesquisa
Processo FAPESP: 05/54947-2 - Estudo SABE - 2005: saúde, bem-estar e envelhecimento: estudo longitudinal sobre as condições de vida e saúde dos idosos no município de São Paulo
Beneficiário:Ruy Laurenti
Linha de fomento: Auxílio à Pesquisa - Temático
Processo FAPESP: 99/05125-7 - As condições de saúde dos idosos na América Latina e Caribe
Beneficiário:Ruy Laurenti
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 09/53778-3 - Estudo longitudinal sobre as condições de vida e saúde dos idosos do município de São Paulo - estudo SABE
Beneficiário:Maria Lúcia Lebrão
Linha de fomento: Auxílio à Pesquisa - Temático