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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Use of single-step genome-wide association studies for prospecting genomic regions related to milk production and milk quality of buffalo

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Autor(es):
Barros, Camila da Costa [1] ; de Abreu Santos, Daniel Jordan [1] ; Aspilcueta-Borquis, Rusbel Raul [2] ; Ferreira de Camargo, Gregorio Miguel [3] ; de Araujo Neto, Francisco Ribeiro [4] ; Tonhati, Humberto [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Sao Paulo State Univ, UNESP, FCAV, Jaboticabal, SP - Brazil
[2] Fundacao Univ Fed Grande Dourados, Dourados, MS - Brazil
[3] Univ Fed Bahia, Salvador, BA - Brazil
[4] Inst Fed Goiano, Rio Verde, Go - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF DAIRY RESEARCH; v. 85, n. 4, p. 402-406, NOV 2018.
Citações Web of Science: 0
Resumo

The aim of this research communication was to identify chromosome regions and genes that could be related to milk yield (MY), milk fat (%F) and protein percentage (%P) in Brazilian buffalo cows using information from genotyped and non-genotyped animals. We used the 90 K Axiom (R) Buffalo Genotyping array. A repeatability model was used. An iterative process was performed to calculate the weights of markers as a function of the squared effects of Single Nucleotide Polymorphism (SNP) and allele frequencies. The 10 SNPs with the largest effects for MY, %F and %P were studied and they explained 7.48, 9.94 and 6.56% of the genetic variance, respectively. These regions harbor genes with biological functions that could be related to the traits analyzed. The identification of such regions and genes will contribute to a better understanding of their influence on milk production and milk quality traits of buffaloes. (AU)

Processo FAPESP: 13/24427-3 - Seleção genômica para características de produção e qualidade do leite de búfalas
Beneficiário:Camila da Costa Barros
Linha de fomento: Bolsas no Brasil - Doutorado