Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Neuropsychological and neuroimaging evidences of cerebral dysfunction in stroke-free patients with atrial fibrillation: A review

Texto completo
Autor(es):
Silva, D. S. [1, 2] ; Coan, A. C. [3, 2] ; Avelar, W. M. [1, 2]
Número total de Autores: 3
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Stroke Ctr, Dept Neurol, Campinas, SP - Brazil
[2] Univ Estadual Campinas, BRAINN, Brazilian Inst Neurosci & Neurotechnol, Campinas, SP - Brazil
[3] Univ Estadual Campinas, Neuroimaging Lab, Dept Neurol, Campinas, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo de Revisão
Fonte: JOURNAL OF THE NEUROLOGICAL SCIENCES; v. 399, p. 172-181, APR 15 2019.
Citações Web of Science: 0
Resumo

Atrial fibrillation (AF) is the most common heart arrhythmia, with the highest prevalence in the elderly. AF has been correlated with silent lesions and cognitive impairment, even in the absence of stroke. The cognitive impairment in AF represents a risk of functional decline, morbidity, mortality and high costs, constituting a public health problem due to the increasing prevalence of this arrhythmia. Cognitive analysis of patients with AF without stroke has shown poor performance in executive, memory and learning functions. The greater loss occurs in speed processing and performance of instrumental tasks leading to functional dependence. Neuroimaging studies have shown both structural and functional abnormalities in individuals with AF even in the absence of cognitive impairment. The mechanisms related to cognitive impairment and cerebral abnormalities in the AF are still a matter of discussion in the literature and, therefore, how to stop its progression is unknown. We reviewed the recent evidence about AF and dementia in patients without stroke, with special emphasis to the reported profile of cognitive dysfunction and the neuroimaging evidence of brain abnormalities. (AU)

Processo FAPESP: 13/07559-3 - Instituto Brasileiro de Neurociência e Neurotecnologia - BRAINN
Beneficiário:Fernando Cendes
Linha de fomento: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
Processo FAPESP: 13/00099-7 - Aprimoramento da técnica de EEG-RMf na avaliação pré-operatória de pacientes com epilepsias focais refratárias
Beneficiário:Ana Carolina Coan
Linha de fomento: Bolsas no Brasil - Pós-Doutorado