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Texto completo
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Autor(es):
Mostrar menos - |
Cremasco Takano, Ana Paula
[1, 2]
;
Justo, Lisie Tocci
[2]
;
dos Santos, Nathalia Villa
[2]
;
Marquezini, Monica Valeria
[2]
;
de Andre, Paulo Afonso
[2]
;
Monteiro da Rocha, Francisco Marcelo
[3]
;
Pasqualucci, Carlos Augusto
[2]
;
Barrozo, Ligia Vizeu
[4]
;
Singer, Julio M.
[5]
;
Saldiva De Andre, Carmen Diva
[5]
;
Nascimento Saldiva, Paulo Hilario
[2, 6]
;
Veras, Mariana Matera
[2]
Número total de Autores: 12
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| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Inst Biomed Sci, Dept Anat, Sao Paulo - Brazil
[2] Univ Sao Paulo, Med Sch FMUSP, Sao Paulo - Brazil
[3] Fed Univ Sao Paulo UNIFESP, Escola Paulista Econ & Negocios EPPEN, Sao Paulo - Brazil
[4] Univ Sao Paulo, Sch Philosophy Literature & Human Sci, Dept Geog, Sao Paulo - Brazil
[5] Univ Sao Paulo, Inst Math & Stat, Sao Paulo - Brazil
[6] Univ Sao Paulo IEA USP, Inst Adv Studies, Sao Paulo - Brazil
Número total de Afiliações: 6
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| Tipo de documento: |
Artigo Científico
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| Fonte: |
Environmental Research;
v. 173,
p. 23-32,
JUN 2019.
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| Citações Web of Science: |
3
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| Resumo |
Many studies have been conducted to evaluate the association between air pollution and adverse health effects using a wide variety of methods to assess exposure. However, the assessment of individual long-term exposure to ambient air pollution is a challenging task and has not been evaluated in a large autopsy study. Our goal was to investigate whether exposure to urban air pollution is associated to the degree of lung anthracosis, considering modifying factors such as personal habits, mobility patterns and occupational activities. We conducted a study in Sao Paulo, Brazil from February 2017 to June 2018, combining epidemiological, spatial analysis and autopsybased approaches. Information about residential address, socio-demographic details, occupation, smoking status, time of residence in the city and time spent commuting was collected via questionnaires applied to the next-ofkin. Images of the pleura surface from upper and lower lobes were used to quantify anthracosis in the lungs. We used multiple regression models to assess the association between the amount of carbon deposits in human lungs, measured by the fraction of pleural anthracosis (FA), and potential explanatory variables. We analyzed 413 cases and our data showed that for each additional hour spent in daily commuting, the ratio FA/(1-FA) is multiplied by 1.05 (95% confidence interval: {[}1.02; 1.08]). The estimated coefficient for daily hours spent in traffic was not considerably affected by the inclusion of socio-demographic variables and smoking habits. We estimate a tobacco equivalent dose of 5 cigarettes per day in a city where annual PM2.5 concentration oscillates around 25 mu g/m(3). Pleural anthracosis is a potential index of lifetime exposure to traffic-derived air pollution. (AU) |
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| Processo FAPESP: |
13/21728-2 - Uso de modernas técnicas de autópsia na investigação de doenças humanas (MODAU)
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| Beneficiário: | Paulo Hilário Nascimento Saldiva |
| Linha de fomento: |
Auxílio à Pesquisa - Temático
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| Processo FAPESP: |
16/03461-7 - Comparação da autópsia minimamente invasiva em relação à autópsia convencional para o diagnóstico post-mortem de neoplasias malignas
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| Beneficiário: | Lisie Tocci Justo Luvizutto |
| Linha de fomento: |
Bolsas no Brasil - Pós-Doutorado
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| Processo FAPESP: |
16/22793-0 - Doença de Alzheimer no epitélio olfatório: correlação com o meio ambiente
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| Beneficiário: | Nathalia Villa dos Santos |
| Linha de fomento: |
Bolsas no Brasil - Pós-Doutorado
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| Processo FAPESP: |
16/23129-7 - Impacto da exposição crônica à poluição atmosférica no envelhecimento do miocárdio
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| Beneficiário: | Ana Paula Cremasco Takano |
| Linha de fomento: |
Bolsas no Brasil - Pós-Doutorado
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