Discovery of Cucumis melo endornavirus by deep sequencing of human stool samples in Brazil

Autor(es):Mostrar menos -

da Costa, Antonio Charlys ^{[1, 2]} ; Leal, Elcio ^[3] ; Gill, Danielle ^{[1, 2]} ; de Padua Milagres, Flavio Augusto ^{[4, 5, 6]} ; Komninakis, Shirley Vasconcelos ^{[7, 8]} ; Brustulin, Rafael ^{[4, 5, 6]} ; Rodrigues Teles, Maria da Aparecida ^{[4, 6]} ; Brito Sayao Lobato, Marcia Cristina Alves ^{[4, 6]} ; das Chagas, Rogerio Togisaki ^{[4, 6]} ; Neves dos Santos Abrao, Maria de Fatima ^{[4, 6]} ; de Deus Alves Soares, Cassia Vitoria ^{[4, 6]} ; Deng, Xutao ^{[9, 10]} ; Delwart, Eric ^{[9, 10]} ; Sabino, Ester Cerdeira ^{[1, 2]} ; Luchs, Adriana ^[11]

Afiliação do(s) autor(es):Mostrar menos -

^[1] Univ Sao Paulo, Fac Med, LIM 46, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Inst Trop Med, Ave Dr Eneas de Carvalho Aguiar 470, BR-05403000 Sao Paulo, SP - Brazil

^[3] Fed Univ Para, Inst Biol Sci, Belem Do Para - Brazil

^[4] Publ Hlth Lab Tocantins State LACEN TO, Palmas - Brazil

^[5] Fed Univ Tocantins, Palmas - Brazil

^[6] Hlth Tocantins, Palmas - Brazil

^[7] Fac Med ABC, Postgrad Program Hlth Sci, Santo Andre - Brazil

^[8] Univ Fed Sao Paulo, Retrovirol Lab, Sao Paulo, SP - Brazil

^[9] Blood Syst Res Inst, San Francisco, CA - USA

^[10] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 - USA

^[11] Adolfo Lutz Inst, Enter Dis Lab, Virol Ctr, Ave Dr Arnaldo 355, BR-01246902 Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: VIRUS GENES; v. 55, n. 3, p. 332-338, JUN 2019.
• Citações Web of Science: 2

Resumo

The nearly complete genome sequences of two Cucumis melo endornavirus (CmEV) strains were obtained using deep sequencing while investigating fecal samples for the presence of gastroenteritis viruses. The Brazilian CmEV BRA/TO-23 (aa positions 116-5027) and BRA/TO-74 (aa positions 26-5057) strains were nearly identical to the reference CmEV CL-01 (USA) and SJ1 (South Korea) strains, showing 97% and 98% of nucleotide and amino acid identity, respectively. Endornaviruses are not known to be associated with human disease and their presence may simply reflect recent dietary consumption. Metagenomic analyses offered an opportunity to identify for the first time in Brazil a newly described endornavirus species. (AU)

• Processo FAPESP: 15/12944-9 - Investigando a evolução de cepas animais de rotavírus infectando humanos
• Beneficiário: Adriana Luchs
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/00021-9 - Metagenômica viral da Dengue, Chikungunya e Zika: acompanhar, explicar e prever a transmissão e distribuição espaço-temporal no Brasil
• Beneficiário: Antonio Charlys da Costa
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 16/01735-2 - Metagenômica viral de Dengue, Chikungunya e Zika vírus: acompanhar, explicar e prever a transmissão e distribuição espaço-temporal no Brasil
• Beneficiário: Ester Cerdeira Sabino
• Modalidade de apoio: Auxílio à Pesquisa - Regular