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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Strategic vaccination of hair sheep against Haemonchus contortus

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Autor(es):
Teixeira, Marcel [1, 2, 3] ; Igor Magalhaes Matos, Antonio Francisco [1, 2, 4] ; Albuquerque, Fernando Henrique M. A. [1] ; Bassetto, Cesar Cristiano [5] ; Smith, William David [6] ; Monteiro, Jomar Patricio [1, 2, 3]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Embrapa Caprinos & Ovinos, Fazenda Tres Lagoas, Rodovia Sobral Groairas Km 04, BR-62010970 Sobral, Ceara - Brazil
[2] Ctr Univ UNINTA, Sobral, Ceara - Brazil
[3] Univ Estadual Vale Acarau, Curso Posgrad Zootecnia, Sobral, Ceara - Brazil
[4] Univ Fed Santa Maria, Curso Posgrad Med Vet, Santa Maria, RS - Brazil
[5] Univ Estadual Julio de Mesquita Filho, UNESP Botucatu, Sao Paulo - Brazil
[6] Moredun Res Inst, Pentlands Sci Pk, Penicuik, Midlothian - Scotland
Número total de Afiliações: 6
Tipo de documento: Artigo Científico
Fonte: Parasitology Research; v. 118, n. 8, p. 2383-2388, AUG 2019.
Citações Web of Science: 0
Resumo

In this study, we evaluated in two trials a protocol designed to protect hair sheep using Barbervax (R), a vaccine containing Haemonchus contortus gut membrane glycoprotein antigens. Results indicated that naturally infected vaccinated sheep had significant egg count reductions (90.2 +/- 4.03%) compared with controls, although blood parameters remained relatively unchanged probably because the level of challenge was low. Vaccination prevented the periparturient rise in egg shedding of ewes, as well as egg shedding in lambs (37.1%). In the second trial, sheep which were experimentally exposed to higher artificial challenge also showed an efficient response to the vaccine as confirmed by high antibody levels and reduced egg counts and worm burdens (87 +/- 5.4% and 79%) respectively. Thus, we believe that the vaccine should be integrated with other management practices for meat hair sheep as it has the advantages of adequate efficacy, reducing anthelmintic utilization and avoiding milk and environmental contamination with chemical residues. (AU)

Processo FAPESP: 15/00221-2 - Vacinação de ovinos contra Haemonchus contortus
Beneficiário:César Cristiano Bassetto
Linha de fomento: Bolsas no Brasil - Pós-Doutorado