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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

An intervention to reduce neuropsychiatric symptoms and caregiver burden in dementia: Preliminary results from a randomized trial of the tailored activity program-outpatient version

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Autor(es):
de Oliveira, Alexandra Martini [1] ; Radanovic, Marcia [1] ; Homem de Mello, Patricia Cotting [2] ; Buchain, Patricia Cardoso [2] ; Vizzotto, Adriana Dias [2] ; Harder, Janaina [3] ; Stella, Florindo [1] ; Piersol, Catherine Verrier [4] ; Gitlin, Laura N. [5] ; Forlenza, Orestes Vicente [1]
Número total de Autores: 10
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Hosp Clin, Lab Neurociencias Lim 27, Fac Med, Inst Psiquiatria, Sao Paulo - Brazil
[2] Univ Sao Paulo, Hosp Clin, Serv Terapia Ocupac, Fac Med, Inst Psiquiatria, Sao Paulo - Brazil
[3] Univ Sao Paulo, Hosp Clin HCFMUSP, Inst Psiquiatria, Fac Med, Sao Paulo - Brazil
[4] Thomas Jefferson Univ, Dept Occupat Therapy, Philadelphia, PA 19107 - USA
[5] Dexel Univ, CNHP, Philadelphia, PA - USA
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY; v. 34, n. 9, SI, p. 1301-1307, SEP 2019.
Citações Web of Science: 2
Resumo

Objective To evaluate the efficacy of the tailored activity program-outpatient version (TAP-O) and to reduce neuropsychiatric symptoms (NPS) in patients with dementia and caregiver burden compared with a control group (psychoeducation intervention). Methods Twenty-one persons with dementia and their caregivers were recruited and randomized. The intervention group received TAP-O, designed for outpatients with dementia and their caregivers. TAP-O consisted of eight sessions in which an occupational therapist assessed the patient's abilities and interests; prescribed tailored activities; and educated caregivers about dementia, NPS, and how to implement meaningful activities in the daily routine. The control group received eight sessions of a psychoeducation intervention about dementia and NPS. Results Compared with controls, patients receiving TAP-O had a significant decrease in hallucination (P = 0.04), agitation (P = 0.03), anxiety (P = 0.02), aggression (P = 0.01), sleep disorder (P = 0.02), aberrant motor behavior (P = 0.02), and in caregiver burden (P = 0.003). Conclusions Findings suggest that TAP-O may be an effective nonpharmacological strategy to reduce NPS of outpatients with dementia and to minimize caregiver burden. (AU)

Processo FAPESP: 09/52825-8 - Neurobiologia da doença de Alzheimer: marcadores de risco, prognóstico e resposta terapêutica
Beneficiário:Wagner Farid Gattaz
Linha de fomento: Auxílio à Pesquisa - Temático
Processo FAPESP: 16/01302-9 - Identificação das vias direta e indireta da inibição da glicogênio sintase kinase 3B pelo lítio em cultura de neurônios
Beneficiário:Vanessa de Jesus Rodrigues de Paula
Linha de fomento: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 14/14211-6 - Comprimento telomérico no sistema nervoso central de um modelo de Doença de Alzheimer tratado com lítio
Beneficiário:Giancarlo de Mattos Cardillo
Linha de fomento: Bolsas no Brasil - Mestrado