Human sapovirus GI.2 and GI.3 from children with acute gastroenteritis in northern Brazil

Autor(es):Mostrar menos -

Audrey Cilli ^[1] ; Adriana Luchs ^[2] ; Elcio Leal ^[3] ; Danielle Gill ; Flavio Augusto de Pádua Milagres ; Shirley Vasconcelos Komninakis ; Rafael Brustulin ; Maria da Aparecida Rodrigues Teles ; Márcia Cristina Alves Brito Sayão Lobato ; Rogério Togisaki das Chagas ; Maria de Fátima Neves dos Santos Abrão ; Cassia Vitória de Deus Alves Soares ; Xutao Deng ; Eric Delwart ; Ester Cerdeira Sabino ; Antonio Charlys da Costa

Afiliação do(s) autor(es):Mostrar menos -

^[1] Instituto Adolfo Lutz. Centro de Virologia. Núcleo de Doenças Entéricas - Brasil

^[2] Instituto Adolfo Lutz. Centro de Virologia. Núcleo de Doenças Entéricas - Brasil

^[3] Universidade Federal do Pará. Instituto de Ciências Biológicas - Brasil

• Tipo de documento: Artigo Científico
• Fonte: Memórias do Instituto Oswaldo Cruz; v. 114, 2019-04-04.

Resumo

Human sapoviruses (HSaV) are considered important causative agents of acute gastroenteritis in humans worldwide. However, knowledge of the genetic characteristics of the whole genome of HSaV in Brazil is limited. Here we report the complete genome sequences of six HSaVs GI.2 and two GI.3 strains obtained from children with acute gastroenteritis in the Northern region of Brazil. Next generation sequencing was used to obtain the full genome and molecular characterization of the genome was performed. Phylogenetic analysis of the genome was also performed. Only one complete HSaV GI.2 genome characterization in the country precedes that of the present study. This is the first complete genome sequence of genotype GI.3 in Brazil. The data obtained in this investigation can contribute to the augmentation of the database on the molecular diversity of HSaVs strains circulating in Brazil, and to the improvement of current typing protocols. (AU)

• Processo FAPESP: 15/12944-9 - Investigando a evolução de cepas animais de rotavírus infectando humanos
• Beneficiário: Adriana Luchs
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/00021-9 - Metagenômica viral da Dengue, Chikungunya e Zika: acompanhar, explicar e prever a transmissão e distribuição espaço-temporal no Brasil
• Beneficiário: Antonio Charlys da Costa
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 16/01735-2 - Metagenômica viral de Dengue, Chikungunya e Zika vírus: acompanhar, explicar e prever a transmissão e distribuição espaço-temporal no Brasil
• Beneficiário: Ester Cerdeira Sabino
• Modalidade de apoio: Auxílio à Pesquisa - Regular