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(Referência obtida automaticamente do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The first survey of human T-cell lymphotropic viruses (HTLV) in HIV/AIDS patients in Santa Catarina State, Brazil

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Autor(es):
Chaiana Esmeraldino Mendes Marcon ; Karoline Rodrigues Campos ; Gabriela Bassi da Silva ; Fabiana Schuelter-Trevisol ; Aline Daiane Schlindwein ; Daisson José Trevisol ; Adele Caterino-de-Araujo
Número total de Autores: 7
Tipo de documento: Artigo Científico
Fonte: Revista do Instituto de Medicina Tropical de São Paulo; v. 61, p. -, 2019.
Citações Web of Science: 0
Resumo

ABSTRACT Santa Catarina is a Brazilian State that has reported the lowest prevalence of human T-cell lymphotropic viruses (HTLV-1/2) in blood donors (0.04%). Although it presents ports, airports and roads that facilitate the entrance and dissemination of new infectious agents, no information exists concerning the HTLV-1/2 infections in HIV/AIDS patients. This study searched for HTLV-1/2 antibodies in plasma samples of 625 HIV/AIDS patients from the municipality of Tubarao (Southern Santa Catarina), and disclosed 1.1% of positivity (0.48% HTLV-1, 0.48% HTLV-2 and 0.16% untypeable HTLV), and a positive correlation with the male sex (OR 4.16) and intravenous drug use (OR 35.18). Although the percentage of 1.1% appears to be low, it is 27.5 times higher than the percentage detected in blood donors. Since HTLV-1 and HTLV-2 are circulating in HIV-infected individuals in Southern Santa Catarina, and these retroviruses could cause a differently impact on the HIV/AIDS outcomes, the surveillance of HTLV-1/2 is necessary, and it could support public health policies in preventing the transmission and dissemination of these viruses in this State. (AU)

Processo FAPESP: 16/03654-0 - Marcadores genéticos virais e do hospedeiro que podem influenciar o curso da infecção pelo HIV-1 e da coinfecção HIV-1/HTLV-1 e HIV-1/HTLV-2
Beneficiário:Adele Caterino de Araújo
Linha de fomento: Auxílio à Pesquisa - Regular