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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Remineralization of early enamel caries lesions induced by bioactive particles: An in vitro speckle analysis

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Autor(es):
Sfalcin, Ravana Angelini [1] ; Pereira da Silva, Joao Vagner [1] ; Pessoa, Victoria Oliva [2] ; Santos, Jennifer [2] ; Garcia Olivan, Silvia Regina [1] ; Santos Fernandes, Kristianne Porta [1] ; Deana, Alessandro Melo [1] ; Makeeva, Irina [3] ; Sauro, Salvatore [3, 4] ; Bussadori, Sandra Kalil [1, 5]
Número total de Autores: 10
Afiliação do(s) autor(es):
[1] Univ Nove Julho UNINOVE, Postgrad Program Biophoton Appl Hlth Sci & Rehabi, Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil
[2] Univ Nove Julho UNINOVE, Program Biophoton Appl Hlth Sci & Rehabil Sci, Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil
[3] Sechenov Univ, Dept Therapeut Dent, Mozhaisky Val 11, Moscow 119435 - Russia
[4] Univ CEU, Biomat Prevent & Minimally Invas Dent, Dept Odontol, Fac Ciencias Salud, C Pozo S-N, Valencia - Spain
[5] Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: Photodiagnosis and Photodynamic Therapy; v. 28, p. 201-209, DEC 2019.
Citações Web of Science: 0
Resumo

This study aimed at evaluating the remineralization effect promoted by different bioactive fillers on simulated early caries lesions in enamel (ECLE). Forty sound bovine incisors were used to prepare buccal enamel specimens (6 x 6 x 2 mm). The specimens were divided into two areas (3 x 3 mm(2)): control (CTR) and experimental (EXP). All the enamel specimens were then submitted to a specific protocol for a period of 48 h to induce simulated caries lesions. Subsequently, the specimens were treated for 7 days (2 min, twice a day) with a slurry pastes containing different bioactive particles (P/L ratio: 1 g/mL). All the specimens were analyzed by laser speckle before and after treatments. The results showed after the first analysis that the ECLE had very low average intensity (back-scattered light). Conversely, after application of the bioactive pastes, higher average intensity was always detected; this was comparable to CTR sound specimens. In conclusion, innovative pastes/gels developed for enamel remineralization should contain bioactive particles that when applied daily on early caries lesions may ``boost{''} the remineralization process to reestablish a sound enamel. (AU)

Processo FAPESP: 15/25180-7 - Visão computacional aliada a iluminação coerente aplicada a processos de diagnóstico em odontologia
Beneficiário:Alessandro Melo de Ana
Linha de fomento: Auxílio à Pesquisa - Regular