Selection for Growth and Precocity Alters Muscle Metabolism in Nellore Cattle

Autor(es)

Brandao Consolo, Nara Regina ^[1] ; da Silva, Juliana ^[1] ; Macedo Buarque, Vicente Luiz ^[1] ; Higuera-Padilla, Angel ^[2] ; Garibaldi Simon Barbosa, Luis Carlos ^[2] ; Zawadzki, Andressa ^[3] ; Colnago, Luis Alberto ^[2] ; Netto, Arlindo Saran ^[1] ; Gerrard, David Edwin ^[4] ; Silva, Saulo Luz ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dept Anim Sci, Duque de Caxias Norte 225, BR-13635900 Pirassununga - Brazil

^[2] EMBRAPA Instrumentacao, Xv Novembro 1452, BR-13560970 Sao Carlos - Brazil

^[3] Univ Copenhagen, Dept Food Sci, Rolighedsvej 26, DK-1958 Frederiksberg - Denmark

^[4] Virginia Tech, Dept Anim & Poultry Sci, Blacksburg, VA 24061 - USA

• Tipo de documento: Artigo Científico
• Fonte: METABOLITES; v. 10, n. 2 FEB 2020.
• Citações Web of Science: 0

Resumo

To clarify the relationship between beef genetic selection for growth and precocity with muscle metabolism and metabolites, we performed metabolomic analysis using Longissimus lumborum (LL) muscle from Nellore cattle with divergent selection for these traits (high growth, HG; low growth, LG; high precocity, HP; low precocity, LP). Genetic potential for growth affected muscle protein and energetic metabolism. HG animals had a high concentration of arginine, carnosine, and leucine compared to LG animals. HP animals presented a high concentration of glutamine, betaine, creatinine, isoleucine, carnitine, acetyl carnitine, and lower levels of glucose compared to LP animals, affecting protein and fatty acid metabolism. Intensity of selection (high or low) was correlated with changes in protein metabolism, and the type of selection (growth or precocity) affected fat metabolism. In conclusion, both HG and HP appear to be correlated with a high concentration of protein metabolites and changes in protein metabolic pathways, while selection for precocity is more correlated with changes in fat metabolism compared to animals selected for growth. (AU)

• Processo FAPESP: 16/01320-7 - Caracterização metabolômica do plasma e da carne de tourinhos Nelore, filhos de touros com diferentes DEPs para crescimento, precocidade e musculosidade
• Beneficiário: Nara Regina Brandão Cônsolo
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 16/17433-5 - Estudo da relação entre a diferença esperada na progênie (DEP) com características produtivas e de qualidade da carne em bovinos Nelore
• Beneficiário: Saulo da Luz e Silva
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 18/09800-3 - Caracterização metabolômica da carne de ovinos e bovinos
• Beneficiário: Nara Regina Brandão Cônsolo
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado