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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The Sexual Ancestor of all Eukaryotes: A Defense of the ``Meiosis Toolkit{''} A Rigorous Survey Supports the Obligate Link between Meiosis Machinery and Sexual Recombination

Texto completo
Autor(es):
Hofstatter, Paulo G. [1] ; Ribeiro, Giulia M. [1] ; Porfirio-Sousa, Alfredo L. [1] ; Lahr, Daniel J. G. [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Biociencias, Rua Matao, Travessa 14, A101, BR-05508090 Sao Paulo - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: BIOESSAYS; v. 42, n. 9 JUL 2020.
Citações Web of Science: 0
Resumo

The distribution pattern of the meiotic machinery in known eukaryotes is most parsimoniously explained by the hypothesis that all eukaryotes are ancestrally sexual. However, this assumption is questioned by preliminary results, in culture conditions. These suggested thatAcanthamoeba, an organism considered to be largely asexual, constitutively expresses meiosis genes nevertheless-at least in the lab. This apparent disconnect between the ``meiosis toolkit{''} and sexual processes inAcanthamoebaled to the conclusion that the eukaryotic ancestor is asexual. In this review, the ``meiosis toolkit{''} is rigorously defended, drawing on numerous research articles. Additionally, the claim of constitutive meiotic gene expression is probed inAcanthamoebavia the same transcriptomics data. The results show that the expression of the meiotic machinery is not constitutive inAcanthamoebaas claimed before. Furthermore, it is argued that this would have no implications for understanding the nature of the eukaryotic ancestor, regardless of the result. (AU)

Processo FAPESP: 19/22109-0 - Avaliação do impacto de condições ambientais na diversidade taxonômica e funcional de tecamebas
Beneficiário:Giulia Magri Ribeiro
Linha de fomento: Bolsas no Brasil - Doutorado