Malaria transmission in landscapes with varying deforestation levels and timelines in the Amazon: a longitudinal spatiotemporal study

Autor(es):Mostrar menos -

Laporta, Gabriel Z. ^[1] ; Ilacqua, Roberto C. ^[1] ; Bergo, Eduardo S. ^[2] ; Chaves, Leonardo S. M. ^[3] ; Rodovalho, Sheila R. ^[4] ; Moresco, Gilberto G. ^[5] ; Figueira, Elder A. G. ^[6] ; Massad, Eduardo ^[7] ; de Oliveira, Tatiane M. P. ^[3] ; Bickersmith, Sara A. ^[8] ; Conn, Jan E. ^{[9, 8]} ; Sallum, Maria Anice M. ^[3]

Afiliação do(s) autor(es)

^[1] Fundacao ABC, Ctr Univ Saude ABC FMABC, Setor Posgrad Pesquisa & Inovacao, Santo Andre, SP - Brazil

^[2] Secretaria Estado Saude Sao Paulo, Superintendencia Controle Endemias SUCEN, Araraquara, SP - Brazil

^[3] Univ Sao Paulo FSP USP, Dept Epidemiol, Fac Saude Publ, Sao Paulo, SP - Brazil

^[4] Pan Amer Hlth Org PAHO WHO, Unidade Tecn Doencas Transmissiveis & Anal Situac, Brasilia, DF - Brazil

^[5] Minist Saude MS, Coordenacao Geral Vigilancia Zoonoses & Doencas T, Secretaria Vigilancia Saude, Brasilia, DF - Brazil

^[6] Fundacao Vigilancia Saude Amazonas, Manaus, AM - Brazil

^[7] Fundacao Getulio Vargas, Escola Matemat Aplicada, Rio De Janeiro, RJ - Brazil

^[8] New York State Dept Hlth, Wadsworth Ctr, Slingerlands, NY - USA

^[9] SUNY Albany, Dept Biomed Sci, Sch Publ Hlth, Albany, NY 12222 - USA

• Tipo de documento: Artigo Científico
• Fonte: SCIENTIFIC REPORTS; v. 11, n. 1 MAR 19 2021.
• Citações Web of Science: 0

Resumo

The relationship between deforestation and malaria is a spatiotemporal process of variation in Plasmodium incidence in human-dominated Amazonian rural environments. The present study aimed to assess the underlying mechanisms of malarial exposure risk at a fine scale in 5-km(2) sites across the Brazilian Amazon, using field-collected data with a longitudinal spatiotemporally structured approach. Anopheline mosquitoes were sampled from 80 sites to investigate the Plasmodium infection rate in mosquito communities and to estimate the malaria exposure risk in rural landscapes. The remaining amount of forest cover (accumulated deforestation) and the deforestation timeline were estimated in each site to represent the main parameters of both the frontier malaria hypothesis and an alternate scenario, the deforestation-malaria hypothesis, proposed herein. The maximum frequency of pathogenic sites occurred at the intermediate forest cover level (50% of accumulated deforestation) at two temporal deforestation peaks, e.g., 10 and 35 years after the beginning of the organization of a settlement. The incidence density of infected anophelines in sites where the original forest cover decreased by more than 50% in the first 25 years of settlement development was at least twice as high as the incidence density calculated for the other sites studied (adjusted incidence density ratio = 2.25; 95% CI, 1.38-3.68; p= 0.001). The results of this study support the frontier malaria as a unifying hypothesis for explaining malaria emergence and for designing specific control interventions in the Brazilian Amazon. (AU)

• Processo FAPESP: 14/09774-1 - Dinâmica de transmissão de malária em diferentes limiares de fragmentação da paisagem
• Beneficiário: Gabriel Zorello Laporta
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Jovens Pesquisadores
• Processo FAPESP: 14/26229-7 - Genômica de paisagens em gradientes latitudinais e ecologia de Anopheles darlingi
• Beneficiário: Maria Anice Mureb Sallum
• Modalidade de apoio: Auxílio à Pesquisa - Temático