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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Investigation of a modified hydraulic calcium silicate-based material - Bio-C Pulpo

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Autor(es):
Pelepenko, Lauter Eston [1] ; Saavedra, Flavia [1] ; Marconato Antunes, Thiago Bessa [1] ; Bombarda, Gabriela Fernanda [1] ; Figueiredo de Almeida Gomes, Brenda Paula [1] ; Zaia, Alexandre Augusto [1] ; Marciano, Marina Angelica [1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Restorat Dent, UNICAMP, Piracicaba, SP - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: Brazilian Oral Research; v. 35, 2021.
Citações Web of Science: 1
Resumo

This study evaluated the physicochemical, biological, and antimicrobial properties of a new hydraulic calcium silicate-based modified material, and compared it with MTA Repair HP and MTA Angelus. The materials were assessed regarding color luminosity (L), color change, radiopacity, setting time, and ISO 6876:2012 linear flow. Volumetric filling and volume change were evaluated using microcomputed-tomography (mu CT). Chemical characterization after 28 days in Hank's Balanced Salt Solution (HBSS) and pH analysis were also assessed. Biological characterization of cytotoxicity and microbiological assessment were also undertaken. Shapiro-Wilk, ANOVA, Levene and post hoc analyses with Bonferroni correction were performed, adopting a 5% significance level (p <0.05). Bio-C Pulpo exhibited the highest L values after 90 days. All tested materials demonstrated color change during the analyses, and had radiopacity above 5 mm Al. MTA Repair HP set faster than Bio-C Pulpo, whereas the latter had the highest linear flow. MTA Repair HP had the highest volumetric filling in mu CT analysis. Bio-C Pulpo showed the highest alkalinity during all tested periods, and the highest volumetric loss (above 9%), in comparison with MTA Repair HP and MTA Angelus. Bio-C Pulpo did not form calcium hydroxide after hydration. MTA Repair HP demonstrated the highest cytocompatibility, and Bio-C Pulpo, the highest cytotoxicity. No inhibition halos were observed for any material, and similar higher turbidity values were seen after direct contact. Composition additives used in Bio-C Pulpo modified its properties, and both the absence of calcium hydroxide deposition after hydration, and the related cytotoxicity of this material are of particular concern. (AU)

Processo FAPESP: 17/05096-7 - Avaliação das propriedades físicas, químicas e antimicrobianas de um novo cimento reparador de alta plasticidade
Beneficiário:Marina Angélica Marciano da Silva
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 17/18413-0 - Avaliação da bioatividade, escoamento, pH e liberação de íons cálcio de cimentos reparadores de alta plasticidade
Beneficiário:Thiago Bessa Marconato Antunes
Linha de fomento: Bolsas no Brasil - Iniciação Científica
Processo FAPESP: 18/06515-6 - Caracterização química e estrutural de cimentos reparadores de alta plasticidade
Beneficiário:Gabriela Fernanda Bombarda
Linha de fomento: Bolsas no Brasil - Iniciação Científica
Processo FAPESP: 18/16722-9 - Padrões de difração de cimentos reparadores de alta plasticidade
Beneficiário:Gabriela Fernanda Bombarda
Linha de fomento: Bolsas no Exterior - Estágio de Pesquisa - Iniciação Científica