| Texto completo | |
| Autor(es): |
Foratori-Junior, Gerson Aparecido
;
Pereira, Priscilla Ramos
;
Gasparoto, Isabella Antunes
;
Sales-Peres, Silvia Helena de Carvalho
;
de Souza, Juliana Moura Storniolo
;
Khan, Shahrukh
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JAPANESE DENTAL SCIENCE REVIEW; v. 58, p. 11-pg., 2022-11-01. |
| Resumo | |
This systematic review and meta-analysis aimed to generate pooled evidence for the association between excessive weight and pregnancy induced periodontitis. EMBASE, SCOPUS, PubMed/MEDLINE, Web of Science, BVS/LILACS, Cochrane Library and SCIELO databases were accessed. Eligibility criteria were: human clinical studies published between year 2000 and 2021. Newcastle-Ottawa scale was used to evaluate risk of bias of the studies. Meta-analysis was performed using MedCalc (R) Statistical Software. Eleven studies were included, evaluating 2152 pregnant women (743 with overweight/obesity and 1409 with normal body mass index -BMI), with a mean age of 29.62 years. Most studies had low risk of bias. A positive association between overweight/obesity and periodontitis was found, with an average of 61.04% of women with overweight/obesity and periodontitis, showing the overall random-effects relative risk and 95% CI of 2.21 (1.53-3.17) (p < 0.001). Arterial hypertension, gestational diabetes mellitus and excessive gestational weight gain were the most common adverse effects of maternal obesity that may have been linked to periodontitis induced pro-inflammatory state. In conclusion, a positive association was found between overweight/obesity and periodontitis during pregnancy. However, the high heterogeneity between the studies related to sample size, periodontal classification and the cutoff-points for BMI are the main limitation.(c) 2022Published by Elsevier Ltd on behalf of The Japanese Association for Dental Science. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ CC_BY_NC_ND_4.0 (AU) | |
| Processo FAPESP: | 18/20626-5 - Avaliação de proteínas diferencialmente expressas na saliva associadas à periodontite durante o 3º trimestre de gestação em pacientes obesas e eutróficas |
| Beneficiário: | Gerson Aparecido Foratori Junior |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |