Synthesis and evaluation of hollow porous molecularly imprinted polymer for selective determination of tetracycline

Autor(es)

Pupin, Rafael Rovatti ; Taboada Sotomayor, Maria Del Pilar

• Tipo de documento: Artigo Científico
• Fonte: Journal of Materials Science; v. 57, n. 36, p. 13-pg., 2022-09-17.

Resumo

A novel hollow porous molecularly imprinted polymer (HMIP) was synthesized for tetracycline determination in different matrices and the adsorption efficiency of this material was compared with the widely applied traditional (unmodified) and core-shell MIP structures. For this purpose, three different tetracycline imprinted polymers were obtained: with the reagent conditions optimized from traditional MIP, a core-shell MIP was obtained by surface polymerization of SiO2 nanoparticles (SiO2MIP). Subsequently, the silica core was removed, obtaining the hollow porous MIP. All materials were characterized by different techniques and HMIP presented higher surface area (227 m(2) g(-1)) and pore volume (0.2 cm(3) g(-1)) when compared with MIP (82.3 m(2) g(-1) and 0.09 cm(3) g(-1)) or SiO2@MIP (109 m(2) g(-1) and 0.1 cm(3) g(-1)) and the respective Non-Imprinted Polymers (NIPs). After optimizing the analysis conditions each polymer structure exhibited different kinetics and equilibrium adsorption behavior, which was related to greater or lesser porosity. HMIP presented superior results for the identification of tetracycline in adsorption experiments (maximum binding capacity of 5.6 mg g(-1) and 0.2 L mg(-1) affinity constant) and in selectivity tests. Water, synthetic urine and milk samples fortified with tetracycline were evaluated and HMIP showed recovery in the range of 74-96%. [GRAPHICS] . (AU)

• Processo FAPESP: 14/50945-4 - INCT 2014: Instituto Nacional de Tecnologias Alternativas para Detecção, Avaliação Toxicológica e Remoção de Micropoluentes e Radioativos
• Beneficiário: Maria Valnice Boldrin
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 19/00677-7 - RADes-MIP - preparação e síntese de materiais para desenvolvimento de dispositivos de análise rápida para monitoramento de poluentes emergentes usando polímeros biomiméticos altamente seletivos baseados na tecnologia de impressão molecular
• Beneficiário: Maria Del Pilar Taboada Sotomayor
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/20789-9 - Síntese e aplicação de polímeros molecularmente impressos (MIP) na construção de dispositivos de análise rápida do tipo fluxo lateral para detecção de contaminantes ambientais
• Beneficiário: Rafael Rovatti Pupin
• Modalidade de apoio: Bolsas no Brasil - Doutorado