Post-dynamic, isometric and combined resistance exercise responses in medicated hypertensive men

Autor(es)

Oliveira-Silva, Laura ; Fecchio, Rafael Yokoyama ; da Silva Junior, Natan Daniel ; Pio-Abreu, Andrea ; da Silva, Giovanio Vieira ; Drager, Luciano Ferreira ; de Sousa, Julio Cesar Silva ; de Moraes Forjaz, Claudia Lucia

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF HUMAN HYPERTENSION; v. N/A, p. 10-pg., 2023-09-05.

Resumo

This study investigated the effects of dynamic resistance exercise (DRE), isometric handgrip exercise (IHE) and combined resistance exercise (DRE+IHE) on post-exercise hypotension (PEH) and its hemodynamic, autonomic, and vascular mechanisms. For that, 70 medicated hypertensives men (52 +/- 8 years) were randomly allocated to perform one of the following interventions: DRE (3 sets, 8 exercises, 50% of 1RM), IHE (4 sets, 2 min, 30% of MVC), CRE (DRE+IHE) and control (CON, seated rest). Before and after the interventions, blood pressure (BP), systemic hemodynamics, cardiovascular autonomic modulation and brachial vascular parameters were evaluated. After the DRE and CRE, systolic and mean BP decreased (SBP = -7 +/- 6 and -8 +/- 8 mmHg; MBP -4 +/- 5 and -5 +/- 5 mmHg, respectively, all P < 0.05), vascular conductance increased (+ 0.47 +/- 0.61 and +0.40 +/- 0.47 ml.min(-1).mmHg(-1), respectively, both P < 0.05) and baroreflex sensitivity decreased (-0.15 +/- 0.38 and -0.29 +/- 0.47 ms/mmHg, respectively, both P < 0.05) in comparison to pre-exercise values. No variable presented any significant change after IHE. The responses observed after CRE were similar to DRE and significantly different from CON and IHE. In conclusion, DRE, but not IHE, elicits PEH, which happens concomitantly to skeletal muscle vasodilation and decreased baroreflex sensitivity. Moreover, adding IHE to DRE does not potentiate PEH and neither changes its mechanisms. (AU)

• Processo FAPESP: 18/12390-1 - Efeitos do treinamento resistido dinâmico, isométrico e combinado (dinâmico + isométrico) na função e regulação cardiovascular de repouso e pós-exercício em homens hipertensos medicados
• Beneficiário: Rafael Yokoyama Fecchio
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 19/02649-0 - Efeito hipotensor agudo do exercício resistido dinâmico, isométrico e combinado (dinâmico +isométrico) em homens hipertensos medicados: determinantes hemodinâmicos e mecanismos autonômicos
• Beneficiário: Laura Gomes Oliveira e Silva
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 18/23653-3 - Efeito hipotensor agudo do exercício resistido dinâmico, isométrico e combinado (dinâmico + isométrico) em homens hipertensos medicados: determinantes hemodinâmicos e mecanismos autonômicos
• Beneficiário: Cláudia Lúcia de Moraes Forjaz
• Modalidade de apoio: Auxílio à Pesquisa - Regular