Human monkeypox virus: Detection methods and perspectives for diagnostics

Autor(es)

Stefano, Jessica Santos ; Silva, Luiz Ricardo Guterres e ; Kalinke, Cristiane ; de Oliveira, Paulo Roberto ; Crapnell, Robert D. ; Brazaca, Lais Canniatti ; Bonacin, Juliano Alves ; Campuzano, Susana ; Banks, Craig E. ; Janegitz, Bruno Campos

• Tipo de documento: Artigo Científico
• Fonte: TRAC-TRENDS IN ANALYTICAL CHEMISTRY; v. 167, p. 18-pg., 2023-10-01.

Resumo

The recent outbreak of the zoonotic human caused by the monkeypox virus, in several non-endemic territories, raised concerns about the emergence of a new pandemic. Still concerned about the recent SARS-CoV-2 pandemics, people have been gathering efforts to control the spread of the monkeypox virus. Human Monkeypox is a disease characterized mainly by the skin lesions caused, it is considered an endemic and neglected African disease that has caused several deaths throughout history. However, recently it was detected in more than 28 non-endemic countries, including the United States and European countries. Furthermore, there is still a lack of data on the extent of infection in asymptomatic people, making it a public health problem. In this aspect, rapid and large-scale testing followed by the isolation of infected individuals is one of the most effective ways of prevention known, as the monkeypox vaccine is not widely available. Thus, this review article presents an overview of recent outbreaks of monkeypox, and the detection methods currently available for the control of this disease. Also, we addressed the potential application of modern methods, which are highly attractive and effective alternatives for aiding in monkeypox diagnosis. Furthermore, we discuss the perspective of using diagnosis in regions of difficult access and poor infrastructure to public health and the control of a highly dangerous virus. (AU)

• Processo FAPESP: 17/21097-3 - Interações abelha-agricultura: perspectivas para a utilização sustentável
• Beneficiário: Osmar Malaspina
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático
• Processo FAPESP: 21/07989-4 - Dispositivos eletroquímicos por manufatura aditiva (impressão 3D) para o diagnóstico de doenças virais
• Beneficiário: Cristiane Kalinke
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado
• Processo FAPESP: 22/06145-0 - Obtenção de sensores eletroquímicos melhorados a partir da modificação de eletrodos impressos em 3D com biofilmes obtidos a partir de cera de abelha e nanomateriais de carbono para a detecção de compostos nocivos em mel
• Beneficiário: Jéssica Santos Stefano
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 13/22127-2 - Desenvolvimento de novos materiais estratégicos para dispositivos analíticos integrados
• Beneficiário: Lauro Tatsuo Kubota
• Modalidade de apoio: Auxílio à Pesquisa - Temático