Current Applications of Liposomes for the Delivery... - BV FAPESP
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Current Applications of Liposomes for the Delivery of Vitamins: A Systematic Review

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Autor(es):
Chaves, Matheus A. ; Ferreira, Leticia S. ; Baldino, Lucia ; Pinho, Samantha C. ; Reverchon, Ernesto
Número total de Autores: 5
Tipo de documento: Artigo Científico
Fonte: NANOMATERIALS; v. 13, n. 9, p. 37-pg., 2023-05-05.
Resumo

Liposomes have been used for several decades for the encapsulation of drugs and bioactives in cosmetics and cosmeceuticals. On the other hand, the use of these phospholipid vesicles in food applications is more recent and is increasing significantly in the last ten years. Although in different stages of technological maturity-in the case of cosmetics, many products are on the market-processes to obtain liposomes suitable for the encapsulation and delivery of bioactives are highly expensive, especially those aiming at scaling up. Among the bioactives proposed for cosmetics and food applications, vitamins are the most frequently used. Despite the differences between the administration routes (oral for food and mainly dermal for cosmetics), some challenges are very similar (e.g., stability, bioactive load, average size, increase in drug bioaccessibility and bioavailability). In the present work, a systematic review of the technological advancements in the nanoencapsulation of vitamins using liposomes and related processes was performed; challenges and future perspectives were also discussed in order to underline the advantages of these drug-loaded biocompatible nanocarriers for cosmetics and food applications. (AU)

Processo FAPESP: 22/01236-7 - Vesículas híbridas e sintéticas formadas por vesículas extracelulares e lipossomas para a suplementação de células embrionárias durante a produção in vitro de bovinos
Beneficiário:Matheus Andrade Chaves
Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 19/08345-3 - Processo supercrítico assistido para coencapsulação de curcumina e vitamina D3 em lipossomas
Beneficiário:Matheus Andrade Chaves
Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
Processo FAPESP: 17/10954-2 - Enriquecimento de amido de milho com curcumina e Vitamina D3 coencapsuladas em lipossomas liofilizados utilizando aglomeração úmida por alto cisalhamento
Beneficiário:Matheus Andrade Chaves
Modalidade de apoio: Bolsas no Brasil - Doutorado