Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Enzymatic Activity, Sensitivity to Antifungal Drugs and Baccharis dracunculifolia Essential Oil by Candida Strains Isolated from the Oral Cavities of Breastfeeding Infants and in Their Mothers' Mouths and Nipples

Texto completo
Autor(es):
Pereira, Cristiane Aparecida [1] ; Borges Pereira da Costa, Anna Carolina [1] ; Silva Machado, Ana Karina [1] ; Beltrame Junior, Miltom [2] ; Amorin Costa Zoellner, Maria Stella [3] ; Junqueira, Juliana Campos ; Cardoso Jorge, Antonio Olavo [1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Sao Paulo State Univ UNESP, Sao Jose dos Campos Dent Sch, Lab Microbiol & Immunol, Dept Biosci & Oral Diag, BR-12245000 Sao Paulo - Brazil
[2] UNIVAP, Inst Res & Dev, Sao Paulo - Brazil
[3] Taubate Univ UNITAU, Biosci Inst, Sao Paulo - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Mycopathologia; v. 171, n. 2, p. 103-109, FEB 2011.
Citações Web of Science: 14
Resumo

Candida strains can cause oral candidosis, as well as nipples candidosis and lead to premature weaning or yeast transmission. The aim of this study was to evaluate 51 Candida isolates obtained from the oral cavities of infants during breastfeeding and mothers' oral cavities and nipples, their enzymatic activity and their sensitivity to amphotericin B, fluconazole and Baccharis dracunculifolia essential oil. Among the studied strains, 96.1% produced phospholipase and 78.4% produced proteinase. The antifungal resistance was only observed among isolates of C. albicans, for which three strains showed a resistant activity to fluconazole and one showed a resistant activity to amphotericin B. All strains were sensitive to B. dracunculifolia essential oil with MIC between 0.2 and 6.25 mg/ml. It was concluded that most of the strains showed significant enzymatic activity and were sensitive to amphotericin B and fluconazole. B. dracunculifolia essential oil inhibited the growth of all strains, including the ones resistant to commercial antifungal agents. (AU)

Processo FAPESP: 09/12005-1 - Avaliação da terapia fotodinâmica em Candida albicans in vitro e in vivo
Beneficiário:Anna Carolina Borges Pereira da Costa
Linha de fomento: Bolsas no Brasil - Mestrado
Processo FAPESP: 10/00879-4 - Microrganismos oportunistas em lesões de estomatite protética e influência da terapia fotodinâmica nos fatores de virulência de Candida spp
Beneficiário:Cristiane Aparecida Pereira
Linha de fomento: Bolsas no Brasil - Doutorado