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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Treatment of Obese Adolescents: The Influence of Periodization Models and ACE Genotype

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Autor(es):
Foschini, Denis [1, 2] ; Araujo, Ronaldo C. [3] ; Bacurau, Reury F. P. [4] ; De Piano, Aline [1] ; De Almeida, Sandro S. [3] ; Carnier, June [1] ; Rosa, Thiago D. S. [5] ; De Mello, Marco T. [6] ; Tufik, Sergio [6] ; Damaso, Ana R. [1, 5]
Número total de Autores: 10
Afiliação do(s) autor(es):
[1] Univ Fed Sao Paulo, Post Grad Program Nutr, Paulista Med Sch, UNIFESP EPM, Sao Paulo - Brazil
[2] Metodista Univ Sao Paulo, Fac Hlth, Sao Paulo - Brazil
[3] Univ Fed Sao Paulo, Dept Biophys, Paulista Med Sch, UNIFESP EPM, Sao Paulo - Brazil
[4] EACH USP, Sch Arts Sci & Humanities, Sao Paulo - Brazil
[5] Univ Fed Sao Paulo, Dept Biosci, Paulista Med Sch, UNIFESP EPM, Sao Paulo - Brazil
[6] Univ Fed Sao Paulo, Dept Psychobiol, Paulista Med Sch, UNIFESP EPM, Sao Paulo - Brazil
Número total de Afiliações: 6
Tipo de documento: Artigo Científico
Fonte: OBESITY; v. 18, n. 4, p. 766-772, APR 2010.
Citações Web of Science: 43
Resumo

The aims of the present study were to compare the effects of two periodization models on metabolic syndrome risk factors in obese adolescents and verify whether the angiotensin-converting enzyme (ACE) genotype is important in establishing these effects. A total of 32 postpuberty obese adolescents were submitted to aerobic training (AT) and resistance training (RT) for 14 weeks. The subjects were divided into linear periodization (LP, n = 16) or daily undulating periodization (DUP, n = 16). Body composition, visceral and subcutaneous fat, glycemia, insulinemia, homeostasis model assessment of insulin resistance (HOMA-IR), lipid profiles, blood pressure, maximal oxygen consumption (VO(2max)), resting metabolic rate (RMR), muscular endurance were analyzed at baseline and after intervention. Both groups demonstrated a significant reduction in body mass, BMI, body fat, visceral and subcutaneous fat, total and low-density lipoprotein cholesterol, blood pressure and an increase in fat-free mass, VO(2max), and muscular endurance. However, only DUP promoted a reduction in insulin concentrations and HOMA-IR. It is important to emphasize that there was no statics difference between LP and DUP groups; however, it appears that there may be bigger changes in the DUP than LP group in some of the metabolic syndrome risk factors in obese adolescents with regard to the effect size (ES). Both periodization models presented a large effect on muscular endurance. Despite the limitation of sample size, our results suggested that the ACE genotype may influence the functional and metabolic characteristics of obese adolescents and may be considered in the future strategies for massive obesity control. (AU)

Processo FAPESP: 08/53069-0 - Efeitos do tratamento multidisciplinar em adolescentes obesos com esteatose hepática não alcoólica e sua relação com as adipocitocinas pró e anti-inflamatórias
Beneficiário:Ana Raimunda Dâmaso
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 06/00684-3 - Fatores orexígenos, anorexígenos, pró e anti-inflamatórios: efeitos do programa multidisciplinar para redução da massa corporal em adolescentes obesos
Beneficiário:Ana Raimunda Dâmaso
Linha de fomento: Auxílio à Pesquisa - Regular