Toxoplasma gondii: host-parasite interaction and behavior manipulation

Autor(es)

da Silva, Rodrigo Costa ^[1] ; Langoni, Helio ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ UNESP, Coll Vet Med & Anim Sci FMVZ, Dept Vet Hyg & Anim Sci DHVSP, Sao Paulo - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: Parasitology Research; v. 105, n. 4, p. 893-898, OCT 2009.
• Citações Web of Science: 48

Resumo

Toxoplasma gondii is an obligate intracellular parasite that causes different lesions in men and other warm-blooded animals. Humoral and cellular immune response of the host against the parasite keeps the protozoan in a latent stage, and clinical disease ensues when immunological response is compromised. Brain parasitism benefits the parasite causing behavioral changes in the host, not only in animals but also in humans. Schizophrenia and epilepsy are two neurological disorders that have recently been reported to affect humans coinfected with T. gondii. Further studies based on host-parasite interaction in several wild or domestic warm-blooded species are still necessary in order to better understand parasitism and behavioral changes caused by T. gondii. (AU)

• Processo FAPESP: 06/07198-7 - Genotipagem de amostras de Toxoplasma gondii isoladas de ovinos de abatedouro
• Beneficiário: Helio Langoni
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 06/02486-4 - Caracterização genotípica de amostras de Toxoplasma gondii isoladas de ovinos de abatedouro
• Beneficiário: Rodrigo Costa da Silva
• Modalidade de apoio: Bolsas no Brasil - Doutorado